Anti-P70 S6 Kinase beta (phospho T421 + S424)抗体(ab53029)

概述

  • 产品名称Anti-P70 S6 Kinase beta (phospho T421 + S424)抗体
    参阅全部 P70 S6 Kinase beta 一抗
  • 描述
    兔多克隆抗体to P70 S6 Kinase beta (phospho T421 + S424)
  • 特异性Detects endogenous levels of Human p70 S6 Kinase beta only when phosphorylated at threonine 421 or serine 424. (The equivalent residues in other species are: Mouse: Thr444,Ser447; Rat: Thr421,Ser424)
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    A synthetic phosphopeptide derived from human p70 S6 Kinase beta around the phosphorylation site of threonine 421 and serine 424(R-TP-P-V-SP).

  • 阳性对照
    • Extracts from NIH/3T3 cells, treated with EGF (200ng/ml, 30mins).

性能

应用

Our Abpromise guarantee covers the use of ab53029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 80 kDa.
ELISA 1/10000.

靶标

  • 功能Phosphorylates specifically ribosomal protein S6.
  • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 70 kDa ribosomal protein S6 kinase 2 antibody
    • EC 2.7.11.1 antibody
    • KS6B2_HUMAN antibody
    • p70 beta antibody
    • p70 ribosomal S6 kinase beta antibody
    • p70 S6 kinase beta antibody
    • p70 S6K-beta antibody
    • p70 S6KB antibody
    • p70 S6Kbeta antibody
    • p70(S6K) beta antibody
    • p70-beta antibody
    • p70-S6K 2 antibody
    • P70S6K2 antibody
    • p70S6Kb antibody
    • Ribosomal protein S6 kinase 70kDa, polypeptide 2 antibody
    • Ribosomal protein S6 kinase beta 2 antibody
    • Ribosomal protein S6 kinase beta-2 antibody
    • Rps6kb2 antibody
    • S6 kinase related kinase antibody
    • S6 kinase-related kinase antibody
    • S6K beta 2 antibody
    • S6K beta antibody
    • S6K-beta antibody
    • S6K-beta-2 antibody
    • S6K2 antibody
    • Serine/threonine protein kinase 14 beta antibody
    • Serine/threonine-protein kinase 14B antibody
    • SRK antibody
    • STK14B antibody
    see all

Anti-P70 S6 Kinase beta (phospho T421 + S424) antibody 图像

  • All lanes : Anti-P70 S6 Kinase beta (phospho T421 + S424) antibody (ab53029) at 1/500 dilution

    Lane 1 : NIH 3T3 cell extract treated with EGF (200ng/ml, 30mins) with immunising peptide
    Lane 2 : NIH 3T3 cell extract treated with EGF (200ng/ml, 30mins)


    Observed band size : 79 kDa (why is the actual band size different from the predicted?)

Anti-P70 S6 Kinase beta (phospho T421 + S424) antibody (ab53029)参考文献

ab53029 has not yet been referenced specifically in any publications.

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