RabMAb

Anti-P70 S6 Kinase beta (phospho S371)抗体[EPR2132] (ab109393)

概述

  • 产品名称Anti-P70 S6 Kinase beta (phospho S371)抗体[EPR2132]
    参阅全部 P70 S6 Kinase beta 一抗
  • 描述
    兔单克隆抗体[EPR2132] to P70 S6 Kinase beta (phospho S371)
  • 特异性This antibody only detects p70 S6 Kinase phosphorylated at serine 371.
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A phospho specific peptide corresponding to residues surrounding serine 371 of Human p70 S6 Kinase.

  • 阳性对照
    • 293T cell lysate treated with Alkaline Phosphatase (AP).
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab109393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 53 kDa.
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Phosphorylates specifically ribosomal protein S6.
    • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 70 kDa ribosomal protein S6 kinase 2 antibody
      • EC 2.7.11.1 antibody
      • KS6B2_HUMAN antibody
      • p70 beta antibody
      • p70 ribosomal S6 kinase beta antibody
      • p70 S6 kinase beta antibody
      • p70 S6K-beta antibody
      • p70 S6KB antibody
      • p70 S6Kbeta antibody
      • p70(S6K) beta antibody
      • p70-beta antibody
      • p70-S6K 2 antibody
      • P70S6K2 antibody
      • p70S6Kb antibody
      • Ribosomal protein S6 kinase 70kDa, polypeptide 2 antibody
      • Ribosomal protein S6 kinase beta 2 antibody
      • Ribosomal protein S6 kinase beta-2 antibody
      • Rps6kb2 antibody
      • S6 kinase related kinase antibody
      • S6 kinase-related kinase antibody
      • S6K beta 2 antibody
      • S6K beta antibody
      • S6K-beta antibody
      • S6K-beta-2 antibody
      • S6K2 antibody
      • Serine/threonine protein kinase 14 beta antibody
      • Serine/threonine-protein kinase 14B antibody
      • SRK antibody
      • STK14B antibody
      see all

    Anti-P70 S6 Kinase beta (phospho S371) antibody [EPR2132] 图像

    • All lanes : Anti-P70 S6 Kinase beta (phospho S371) antibody [EPR2132] (ab109393) at 1/1000 dilution

      Lane 1 : 293T cell lysate, untreated
      Lane 2 : 293T cell lysate, treated with Alkaline Phosphatase (AP)

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 53 kDa

    Anti-P70 S6 Kinase beta (phospho S371) antibody [EPR2132] (ab109393)参考文献

    This product has been referenced in:
    • Mei W  et al. Gambogenic acid kills lung cancer cells through aberrant autophagy. PLoS One 9:e83604 (2014). WB ; Human . Read more (PubMed: 24427275) »
    • Xu R  et al. The protease Omi regulates mitochondrial biogenesis through the GSK3ß/PGC-1a pathway. Cell Death Dis 5:e1373 (2014). WB ; Mouse . Read more (PubMed: 25118933) »

    See all 4 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"