Anti-P70 S6 Kinase beta (phospho S371)抗体(ab60947)

概述

  • 产品名称Anti-P70 S6 Kinase beta (phospho S371)抗体
    参阅全部 P70 S6 Kinase beta 一抗
  • 描述
    兔多克隆抗体to P70 S6 Kinase beta (phospho S371)
  • 特异性ab60947 detects endogenous levels of P70 S6 Kinase beta only when phosphorylated at serine 371.
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from human P70 S6 Kinase beta around the phosphorylation site of serine 371 (V-D-SP-P-D).

  • 阳性对照
    • Human breast carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab60947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. PubMed: 23874880
ELISA 1/50 - 1/100.
IHC-P 1/50 - 1/100.

靶标

  • 功能Phosphorylates specifically ribosomal protein S6.
  • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 70 kDa ribosomal protein S6 kinase 2 antibody
    • EC 2.7.11.1 antibody
    • KS6B2_HUMAN antibody
    • p70 beta antibody
    • p70 ribosomal S6 kinase beta antibody
    • p70 S6 kinase beta antibody
    • p70 S6K-beta antibody
    • p70 S6KB antibody
    • p70 S6Kbeta antibody
    • p70(S6K) beta antibody
    • p70-beta antibody
    • p70-S6K 2 antibody
    • P70S6K2 antibody
    • p70S6Kb antibody
    • Ribosomal protein S6 kinase 70kDa, polypeptide 2 antibody
    • Ribosomal protein S6 kinase beta 2 antibody
    • Ribosomal protein S6 kinase beta-2 antibody
    • Rps6kb2 antibody
    • S6 kinase related kinase antibody
    • S6 kinase-related kinase antibody
    • S6K beta 2 antibody
    • S6K beta antibody
    • S6K-beta antibody
    • S6K-beta-2 antibody
    • S6K2 antibody
    • Serine/threonine protein kinase 14 beta antibody
    • Serine/threonine-protein kinase 14B antibody
    • SRK antibody
    • STK14B antibody
    see all

Anti-P70 S6 Kinase beta (phospho S371) antibody 图像

  • ab60947 at 1/50 - 1/100 dilution staining P70 S6 Kinase beta in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-P70 S6 Kinase beta (phospho S371) antibody (ab60947)参考文献

This product has been referenced in:
  • Fei SJ  et al. Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells. PLoS One 8:e69104 (2013). WB, IHC ; Human . Read more (PubMed: 23874880) »

See 1 Publication for this product

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