Anti-p63蛋白+ HMW Cytokeratin抗体[4A4,34] (ab58514)
Key features and details
- Mouse monoclonal [4A4, 34] to p63 Protein + HMW Cytokeratin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
-
产品名称
Anti-p63蛋白+ HMW Cytokeratin抗体[4A4,34] -
描述
小鼠单克隆抗体[4A4,34] to p63蛋白+ HMW Cytokeratin -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human p63 Protein + HMW Cytokeratin.
-
阳性对照
- Normal prostate tissue or skin
-
常规说明
ab58514 isotypes: IgG2a + IgG1The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
-
克隆
单克隆 -
克隆编号
4A4, 34 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab58514于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
说明 |
---|
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
-
相关性
The p63 and high molecular weight cytokeratin cocktail is a marker for basal cells. The p63 protein, a homologue of the tumour-suppressor p53, is highly expressed in the nuclei of basal or progenitor layer of many epithelial tissues. p63 is detected in prostate basal cells in normal prostate glands and PIN. Other markers for basal cells are high molecular cytokeratins (CK 1, 5, 10 and 14). The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. -
细胞定位
Cytoplasmic and Nuclear -
数据库链接
- Entrez Gene: 3860 Human
- Entrez Gene: 3861 Human
- Entrez Gene: 3866 Human
- Entrez Gene: 3868 Human
- Entrez Gene: 8626 Human
- SwissProt: P02533 Human
- SwissProt: P08779 Human
- SwissProt: P13646 Human
see all -
别名
- CK13 antibody
- CK14 antibody
- CK15 antibody
see all
数据表及文件
-
Datasheet download
文献 (0)
ab58514 尚未被引用在任何文献中。