概述

  • 产品名称Anti-P4HA3抗体
    参阅全部 P4HA3 一抗
  • 描述
    兔多克隆抗体to P4HA3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to internal sequence amino acids 130-396 of Human P4HA3 (BC117333).

  • 阳性对照
    • Human fetal kidney & liver lysates, Human fetal liver tissue.

性能

  • 形式Lyophilised:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab101657 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 61 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
  • 组织特异性Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions.
  • 序列相似性Belongs to the P4HA family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 1 TPR repeat.
  • 翻译后修饰N-glycosylation plays no role in the catalytic activity.
  • 细胞定位Endoplasmic reticulum lumen.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2-oxoglutarate-4-dioxygenase subunit alpha-3 antibody
    • 4-PH alpha-3 antibody
    • P4ha3 antibody
    • P4HA3_HUMAN antibody
    • Procollagen-proline antibody
    • Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III antibody
    • Procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha subunit, isoform 3 antibody
    • Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3 antibody
    • Prolyl 4-hydroxylase subunit alpha-3 antibody
    • Prolyl 4-hydroxylase, alpha polypeptide III antibody
    • Prolyl 4-hydroxylase, alpha-3 subunit antibody
    see all

Anti-P4HA3 antibody 图像

  • All lanes : Anti-P4HA3 antibody (ab101657) at 1/500 dilution

    Lane 1 : Human fetal kidney lysate
    Lane 2 : Human fetal liver lysate


    Predicted band size : 61 kDa
  • ab101657 at 1/100 dilution staining P4HA3 in Human fetal liver by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-P4HA3 antibody (ab101657)参考文献

This product has been referenced in:
  • Akamatsu T  et al. Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences. Fibrogenesis Tissue Repair 6:15 (2013). IHC-P . Read more (PubMed: 23927729) »

See 1 Publication for this product

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