概述

  • 产品名称
  • 描述
    兔多克隆抗体to P2Y9
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Hamster, Gorilla, Common marmoset, Bat
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region from the C-terminal cytoplasmic domain of Human P2Y9.

  • 阳性对照
    • Human Brain, Cortex tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.01% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use at an assay dependent concentration. Predicted molecular weight: 42 kDa. PubMed: 24396418

靶标

  • 功能
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA.
  • 组织特异性
    High expression in ovary. Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus and hippocampus.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5730485F04Rik antibody
    • G protein coupled receptor 23 antibody
    • G-protein coupled receptor 23 antibody
    • GPR23 antibody
    • LPA receptor 4 antibody
    • LPA-4 antibody
    • LPA4 antibody
    • Lpar4 antibody
    • LPAR4_HUMAN antibody
    • Lysophosphatidic acid receptor 4 antibody
    • Lysophosphatidic Acid Receptor P2Y9 antibody
    • P2RY9 antibody
    • P2Y purinoceptor 9 antibody
    • P2Y5 like antibody
    • P2Y5-like receptor antibody
    • P2Y9 antibody
    • Purinergic receptor 9 antibody
    • Purinergic receptor, P2Y, G-protein coupled, 9 antibody
    see all

图片

  • ab115454, at 20 µg/ml, staining P2Y9 in formalin-fixed, paraffin-embedded Human Brain, Cortex tissue by Immunohistochemistry, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

文献

This product has been referenced in:
  • Feng Y & Liu JF Expression of lysophosphatidic acid receptors in the human lower esophageal sphincter. Exp Ther Med 7:423-428 (2014). WB ; Human . Read more (PubMed: 24396418) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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