概述

  • 产品名称Anti-P2X2抗体
    参阅全部 P2X2 一抗
  • 描述
    兔多克隆抗体to P2X2
  • 经测试应用适用于: WB, IHC-Fr, ICC, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse, Guinea pig, Non Human Primates
  • 免疫原

    Synthetic peptide:

    DSTSTDPKGLAQL

    , corresponding to amino acids 460-472 of Rat P2X2.

性能

应用

Our Abpromise guarantee covers the use of ab10266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 47,8 kDa.
IHC-Fr 1/1000.
ICC 1/1000.
IHC-P Use at an assay dependent concentration. PubMed: 21969132

靶标

  • 功能Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
  • 疾病相关Deafness, autosomal dominant, 41
  • 序列相似性Belongs to the P2X receptor family.
  • 细胞定位Cell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
  • Information by UniProt
  • 数据库链接
  • 形式There are 7 isoforms produced by alternative splicing.
  • 别名
    • ATP receptor antibody
    • MGC129601 antibody
    • P2RX 2 antibody
    • P2RX2 antibody
    • P2RX2_HUMAN antibody
    • P2X purinoceptor 2 antibody
    • P2X Receptor subunit 2 antibody
    • P2X2 antibody
    • P2X2a antibody
    • Purinergic receptor antibody
    • Purinergic receptor P2X ligand gated ion channel 2 antibody
    • Purinergic receptor P2X2 isoform A antibody
    • Purinergic receptor P2X2 isoform B antibody
    • Purinergic receptor P2X2 isoform C antibody
    • Purinergic receptor P2X2 isoform D antibody
    • Purinergic receptor P2X2 isoform H antibody
    • Purinergic receptor P2X2 isoform I antibody
    see all

Anti-P2X2 antibody 图像

  • ab10266, at a dilution of 1/1000, staining P2X2 in rat brain stem by Immunohistochemistry (PFA perfusion fixed frozen sections).

Anti-P2X2 antibody (ab10266)参考文献

This product has been referenced in:
  • Kútna V  et al. Enigmatic cerebrospinal fluid-contacting neurons arise even after the termination of neurogenesis in the rat spinal cord during embryonic development and retain their immature-like characteristics until adulthood. Acta Histochem N/A:N/A (2013). Read more (PubMed: 24063862) »
  • Wu T  et al. Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter. Am J Physiol Heart Circ Physiol 301:H69-78 (2011). Read more (PubMed: 21460192) »

See all 3 Publications for this product

Product Wall

Thank you for your inquiry.

As you correctly suspected, we do not know the concentration of the antibody.

Antibody concentration is usually measured by measuring the protein content. Since there are many different proteins in whole ...

Read More

Thank you for your inquiry. To our knowledge, ab10266 has not yet been tested in flow cytometry. It is possible that this product may be suitable for your experiment since it has been successfully used in ICC, but we don't have any data regarding its ...

Read More

Thank you for your enquiry. Antibodies ab10262 and ab10266 are raised against the same peptide which, according to the map found at the link to the SwissProt entry with accession number P49653, is found on a cytoplasmic domain of the protein. I h...

Read More

Thank you for your enquiry and for your patience. The epitopes are intracellular for both ab10266 and ab10267. So unfortunately, they will not suit your needs. If you have any more questions, please contact us again.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"