Anti-P Glycoprotein抗体[UIC2] (Phycoerythrin) (ab93590)


  • 产品名称
    Anti-P Glycoprotein抗体[UIC2] (Phycoerythrin)
    参阅全部 P Glycoprotein 一抗
  • 描述
    小鼠单克隆抗体[UIC2] to P Glycoprotein (Phycoerythrin)
  • 宿主
  • 偶联物
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Mouse Balb/c 3T3 fibroblasts transfected with Human P Glycoprotein cDNA

  • 阳性对照
    • 8226 DOX40 and 8226/S cell lines
  • 常规说明

    ab93590 has been reported to inhibit MDR1-mediated efflux.



Our Abpromise guarantee covers the use of ab93590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 5µl for 106 cells.

Use 5 µl/test for 105-8 cells in 100µl.





ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.



  • 功能
    Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
  • 组织特异性
    Expressed in liver, kidney, small intestine and brain.
  • 疾病相关
    Genetic variations in ABCB1 are associated with susceptibility to inflammatory bowel disease type 13 (IBD13) [MIM:612244]. Inflammatory bowel disease is characterized by a chronic relapsing intestinal inflammation. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Crohn disease and ulcerative colitis are commonly classified as autoimmune diseases.
  • 序列相似性
    Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • 细胞定位
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABC20 antibody
    • ABCB1 antibody
    • ATP binding cassette, sub family B (MDR/TAP), member 1 antibody
    • ATP-binding cassette sub-family B member 1 antibody
    • CD243 antibody
    • CLCS antibody
    • Colchicin sensitivity antibody
    • Doxorubicin resistance antibody
    • GP170 antibody
    • MDR1 antibody
    • MDR1_HUMAN antibody
    • Multidrug resistance 1 antibody
    • Multidrug resistance protein 1 antibody
    • P glycoprotein 1 antibody
    • P gp antibody
    • P-glycoprotein 1 antibody
    • PGY1 antibody
    see all


  • Staining of the 8226/S (blue histogram) and 8226 DOX40 (purple histogram) cell lines with PE Mouse IgG2a, K Isotype Control (left) or ab93590 (right). Total viable cells were used for analysis.


This product has been referenced in:
  • Wang CW  et al. 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. Oncotarget 8:66033-66050 (2017). Read more (PubMed: 29029490) »
  • Huang XC  et al. Parguerenes: Marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells. Biochem Pharmacol 85:1257-68 (2013). Read more (PubMed: 23415901) »

See all 4 Publications for this product


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Please buy ab91363.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for your inquiry.

I am happy to confirm that ab93590 (the isotype control for it (ab1282) will not bind anything specifically, but mark the background staining) is suitable for flow cytometry. It will recognise P-glycoprotein 1 (Pgp...

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Thank you for your enquiry and your interest.

I can confirm that ab93590has been testedin Flow cytometry and ab1282 can be used as isotype control.

We also have other primary antibodies against P Glycoprotein, here are some non-conj...

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Merci pour votre enquête ainsi que pour votre patience pendant que je contactais le laboratoire. Le laboratoire m'a pu répondre que la concentration de cet anticorps est d'environ 0.5ug par 5ul. Donc ceci fait 0.1mg/ml. Le laboratoire à testé 5ul de ce...

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