概述

  • 产品名称Anti-P cadherin抗体
    参阅全部 P cadherin 一抗
  • 描述
    兔多克隆抗体to P cadherin
  • 经测试应用适用于: WB, IHC-P, ICCmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Synthetic peptide corresponding to a sequence at the middle region of human P-Cadherin, different from the mouse and rat sequence by one amino acid.

  • 阳性对照
    • recombinant Human P cadherin

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservatives: 0.02% Sodium azide, 0.01% Thimerosal (merthiolate)
    Constituents: 0.05% BSA, Sodium chloride, 0.01% Monobasic dihydrogen sodium phosphate
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.
IHC-P Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC Use a concentration of 1 µg/ml.

靶标

  • 功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 组织特异性Expressed in some normal epithelial tissues and in some carcinoma cell lines.
  • 疾病相关Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.
    Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.
  • 序列相似性Contains 5 cadherin domains.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CADH3_HUMAN antibody
    • Cadherin 3 antibody
    • Cadherin 3 precursor antibody
    • Cadherin 3 type 1 antibody
    • Cadherin-3 antibody
    • Cadp antibody
    • Calcium dependent adhesion protein placental antibody
    • CDH 3 antibody
    • CDH3 antibody
    • CDH3 protein antibody
    • CDHP antibody
    • HJMD antibody
    • P cadherin (placental) antibody
    • P-cadherin antibody
    • PCAD antibody
    • Placental cadherin antibody
    see all

Anti-P cadherin antibody 图像

  • All lanes : Anti-P cadherin antibody (ab111010) at 1 µg/ml

    Lane 1 : Recombinant P cadherin protein at 0.01 µg
    Lane 2 : Recombinant P cadherin protein at 0.005 µg
    Lane 3 : Recombinant P cadherin protein at 0.0025 µg
    Lane 4 : MK (55KD)


    Predicted band size : 22 kDa

Anti-P cadherin antibody (ab111010)参考文献

ab111010 has not yet been referenced specifically in any publications.

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