Anti-P cadherin抗体[56C1], prediluted (ab75442)


  • 产品名称Anti-P cadherin抗体[56C1], prediluted
    参阅全部 P cadherin 一抗
  • 描述
    小鼠单克隆抗体[56C1] to P cadherin, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein corresponding to extracellular domain of human P cadherin.

  • 表位External domain
  • 阳性对照
    • Human tonsil tissue



Our Abpromise guarantee covers the use of ab75442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.


  • 功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 组织特异性Expressed in some normal epithelial tissues and in some carcinoma cell lines.
  • 疾病相关Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.
    Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.
  • 序列相似性Contains 5 cadherin domains.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CADH3_HUMAN antibody
    • Cadherin 3 antibody
    • Cadherin 3 precursor antibody
    • Cadherin 3 type 1 antibody
    • Cadherin-3 antibody
    • Cadp antibody
    • Calcium dependent adhesion protein placental antibody
    • CDH 3 antibody
    • CDH3 antibody
    • CDH3 protein antibody
    • CDHP antibody
    • HJMD antibody
    • P cadherin (placental) antibody
    • P-cadherin antibody
    • PCAD antibody
    • Placental cadherin antibody
    see all

Anti-P cadherin antibody [56C1], prediluted 图像

  • Formalin-fixed, paraffin-embedded human tonsil stained with ab75442 using peroxidase conjugate and AEC chromogen. Note membrane staining of epithelial cells.

Anti-P cadherin antibody [56C1], prediluted (ab75442)参考文献

ab75442 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply.

I have contacted the lab about adding the undiluted version of ab75442 to the catalogue and I will let you know as soon as I can whether we are able to do this or not.

In the meantime if there is anything e...

Read More
Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (tonsil)
Specification tonsil
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: EDTA, 20 minutes 100C
Permeabilization No

Abcam user community

Verified customer

提交于 Dec 16 2009