概述

  • 产品名称Anti-OTOA抗体
  • 描述
    兔多克隆抗体to OTOA
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 99-127 of Human OTOA (NP_733764.1, NP_001155155.1).

  • 阳性对照
    • Mouse liver tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab107640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 129 kDa.

靶标

  • 功能May act as an adhesion molecule.
  • 疾病相关Defects in OTOA are the cause of deafness autosomal recessive type 22 (DFNB22) [MIM:607039]. DFNB22 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • 序列相似性Belongs to the stereocilin family.
  • 细胞定位Apical cell membrane. Secreted > extracellular space > extracellular matrix. At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cancer/testis antigen 108 antibody
    • CT108 antibody
    • Deafness, autosomal recessive 22 antibody
    • DFNB22 antibody
    • FLJ32773 antibody
    • MGC157747 antibody
    • MGC39813 antibody
    • OTOA antibody
    • OTOAN_HUMAN antibody
    • Otoancorin antibody
    see all

Anti-OTOA antibody 图像

  • Anti-OTOA antibody (ab107640) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 129 kDa

Anti-OTOA antibody (ab107640)参考文献

ab107640 has not yet been referenced specifically in any publications.

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