Anti-Osteopontin抗体[1F11] (ab72526)

概述

  • 产品名称Anti-Osteopontin抗体[1F11]
    参阅全部 Osteopontin 一抗
  • 描述
    小鼠单克隆抗体[1F11] to Osteopontin
  • 特异性ab72526 recognises the C terminal region of Osteopontin
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full Length Recombinant Osteopontin

  • 常规说明IEF: 7.0-7.3

性能

应用

Our Abpromise guarantee covers the use of ab72526 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.
    Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
  • 组织特异性Bone. Found in plasma.
  • 序列相似性Belongs to the osteopontin family.
  • 翻译后修饰Extensively phosphorylated on clustered serine residues.
    N- and O-glycosylated.
    Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BNSP antibody
    • Bone sialoprotein 1 antibody
    • BSP I antibody
    • BSPI antibody
    • Early T lymphocyte activation 1 antibody
    • ETA 1 antibody
    • ETA1 antibody
    • MGC110940 antibody
    • Nephropontin antibody
    • OPN antibody
    • Osteopontin antibody
    • osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein antibody
    • OSTP_HUMAN antibody
    • PSEC0156 antibody
    • secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) antibody
    • Secreted phosphoprotein 1 antibody
    • SPP 1 antibody
    • SPP-1 antibody
    • SPP1 antibody
    • SPP1/CALPHA1 fusion antibody
    • Urinary stone protein antibody
    • Uropontin antibody
    see all

Anti-Osteopontin antibody [1F11] (ab72526)参考文献

This product has been referenced in:
  • Plumer A  et al. Development of fragment-specific osteopontin antibodies and ELISA for quantification in human metastatic breast cancer. BMC Cancer 8:38 (2008). Sandwich ELISA . Read more (PubMed: 18237408) »

See 1 Publication for this product

Product Wall

Thank you for your patience.

I received the following additional information:

For ab53772: This antibody does not bind to the region aa130-170.

For ab72526:Internal data that indicate that the epitope does indeed fall wit...

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Thank you for contacting us.

I have contacted the lab regarding ab72526 and will let you know what I find out.

As for osteopontin antibodies binding to the region of residues 130 to 170:

ab8448 (http://www.abcam.com/Osteo...

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Thank you for contacting us. I was able to speak with the lab and find some more information pertaining to your question about storage buffers. It appears that this is the normal 1x PBS solution made from the 10x recipe that I have included: 168 ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"