Anti-OSBPL2抗体(ab5921)

概述

• 产品名称
  Anti-OSBPL2抗体
  参阅全部 OSBPL2 一抗
• 描述
  山羊多克隆抗体to OSBPL2
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat
• 免疫原

  Synthetic peptide:

  YFERNFSDCPDIY

  , corresponding to C terminal amino acids 468-480 of Human OSBPL2.

  Run BLAST with Run BLAST with
• 常规说明
  GenBank Accession Number – NP_055650; NP_653081

  
  

  This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• 存储溶液
  Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris-saline. pH 7.3
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 纯化说明
  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Primary antibody说明
  This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipid Metabolism
  • Cholesterol Metabolism

  • Signal Transduction
  • Protein Trafficking
  • Vesicle Transport
  • Regulation

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Cholesterol Metabolism

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

应用

靶标

• 相关性
  This gene encodes a member of the oxysterol binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N terminal pleckstrin homology domain and a highly conserved C terminal OSBP like sterol binding domain, although some members contain only the sterol binding domain. This encoded protein contains only the sterol binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3 phosphate, but cannot bind to 25 hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
• 数据库链接
  • Entrez Gene: 9885 Human
  • Entrez Gene: 228983 Mouse
  • Entrez Gene: 296461 Rat
  • Omim: 606731 Human
  • SwissProt: Q9H1P3 Human
  • SwissProt: Q8BX94 Mouse
  • Unigene: 473254 Human
  • Unigene: 253578 Mouse

  • Unigene: 12390 Rat

  see all
• 别名
  • FLJ20223 antibody
  • KIAA0772 antibody
  • MGC4307 antibody

  • MGC8342 antibody
  • ORP2 antibody
  • OSBP related protein 2 antibody
  • Oxysterol binding protein like 2 antibody
  • Oxysterol binding protein related protein 2 antibody

  see all

实验方案

• Western blot protocols