概述
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产品名称Anti-OSBPL2抗体
参阅全部 OSBPL2 一抗 -
描述山羊多克隆抗体to OSBPL2
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宿主Goat
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经测试应用适用于: WBmore details
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种属反应性与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide:
YFERNFSDCPDIY
, corresponding to C terminal amino acids 468-480 of Human OSBPL2. -
常规说明GenBank Accession Number – NP_055650; NP_653081
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris-saline. pH 7.3 -
Concentration information loading... -
纯度Immunogen affinity purified
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纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Primary antibody说明This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab5921 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 55-60 kDa (predicted molecular weight: 55 kDa). |
靶标
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相关性This gene encodes a member of the oxysterol binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N terminal pleckstrin homology domain and a highly conserved C terminal OSBP like sterol binding domain, although some members contain only the sterol binding domain. This encoded protein contains only the sterol binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3 phosphate, but cannot bind to 25 hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
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数据库链接
- Entrez Gene: 9885 Human
- Entrez Gene: 228983 Mouse
- Entrez Gene: 296461 Rat
- Omim: 606731 Human
- SwissProt: Q9H1P3 Human
- SwissProt: Q8BX94 Mouse
- Unigene: 473254 Human
- Unigene: 253578 Mouse
see all -
别名
- FLJ20223 antibody
- KIAA0772 antibody
- MGC4307 antibody
see all
图片
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Western blot - Anti-OSBPL2 antibody (ab5921)ab5921 at 1.5
µ g/ml staining approximately 55-60kDa OSBPL2 in Human Heart Lysate by Western blot (ECL).
ab5921 at 1.5µg/ml staining approximately 55-60kDa OSBPL2 in Human Heart Lysate by Western blot (ECL).
文献
ab5921 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"