概述

  • 产品名称Anti-ORP8抗体
    参阅全部 ORP8 一抗
  • 描述
    小鼠多克隆抗体to ORP8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human ORP8 protein (NP_001003712.1).

  • 阳性对照
    • ORP8 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab70056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 120 kDa (predicted molecular weight: 97 kDa).

靶标

  • 相关性ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.
  • 细胞定位Endoplasmic reticulum
  • 数据库链接
  • 别名
    • DKFZp686A11164 antibody
    • KIAA1451 antibody
    • MGC126578 antibody
    • MGC133203 antibody
    • MST120 antibody
    • MSTP120 antibody
    • ORP 8 antibody
    • OSBP related protein 8 antibody
    • OSBP10 antibody
    • OSBPL8 antibody
    • Oxysterol binding protein like 8 antibody
    • Oxysterol binding protein like protein 8 antibody
    • Oxysterol binding protein related protein 8 antibody
    see all

Anti-ORP8 antibody 图像

  • All lanes : Anti-ORP8 antibody (ab70056) at 1/500 dilution

    Lane 1 : ORP8 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 97 kDa
    Observed band size : 120 kDa (why is the actual band size different from the predicted?)

Anti-ORP8 antibody (ab70056)参考文献

ab70056 has not yet been referenced specifically in any publications.

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