概述

  • 产品名称Anti-Orexin A抗体
    参阅全部 Orexin A 一抗
  • 描述
    羊多克隆抗体to Orexin A
  • 特异性This antibody reacts with Orexin A.
  • 经测试应用适用于: IHC-Fr, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic Orexin A conjugated to KLH.

性能

应用

Our Abpromise guarantee covers the use of ab64565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent dilution.
ELISA 1/200.
IHC-P Use at an assay dependent concentration.

靶标

  • 相关性Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.
  • 细胞定位Rough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction, synapse. Note: Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
  • 数据库链接
  • 别名
    • HCRT antibody
    • HCRT1 antibody
    • HCRT2 antibody
    • hypocretin (orexin) neuropeptide precursor antibody
    • Hypocretin 1 antibody
    • Hypocretin 2 antibody
    • hypocretin antibody
    • NRCLP1 antibody
    • Orexin antibody
    • Orexin A antibody
    • Orexin B antibody
    • Orexin precursor antibody
    • OX antibody
    • PPORX antibody
    • PPOX antibody
    • PREPROOREXIN antibody
    see all

Anti-Orexin A antibody (ab64565)参考文献

ab64565 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab64565.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"