Anti-Oncostatin M抗体(ab110621)

概述

  • 产品名称Anti-Oncostatin M抗体
    参阅全部 Oncostatin M 一抗
  • 描述
    兔多克隆抗体to Oncostatin M
  • 经测试应用适用于: Indirect ELISA, Sandwich ELISA, WB, Neutralisingmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Highly pure (>98%) recombinant Human Oncostatin M.

  • 阳性对照
    • ab110621 was purified by affinity chromatography employing immobilized Human Oncostatin M matrix.

性能

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应用

Our Abpromise guarantee covers the use of ab110621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Indirect ELISA Use a concentration of 0.5 - 2 µg/ml. (using 100 µl/well antibody solution) allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human Oncostatin M.
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Oncostatin M (Biotin) (ab84256). Using ab84256 as the detection antibody and ab110621 as the capture antibody, the detection limit for recombinant Human Oncostatin M is 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 28 kDa. The detection limit for recombinant Human Oncostatin M is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralising Use a concentration of 0.1 - 0.175 µg/ml. to yield one-half maximal inhibition [ND50] of the biological activity of Oncostatin M (10.0 ng/ml)

靶标

  • 功能Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
  • 序列相似性Belongs to the LIF/OSM family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC20461 antibody
    • ONCM_HUMAN antibody
    • Oncostatin M antibody
    • Oncostatin-M antibody
    • OSM antibody
    see all

Anti-Oncostatin M antibody (ab110621)参考文献

ab110621 has not yet been referenced specifically in any publications.

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