Anti-Oncostatin M抗体[17001.31] (ab10842)

概述

  • 产品名称Anti-Oncostatin M抗体[17001.31]
    参阅全部 Oncostatin M 一抗
  • 描述
    小鼠单克隆抗体[17001.31] to Oncostatin M
  • 特异性ab10842 shows < 10% cross-reactivity with recombinant human LIF, but does not cross-react with recombinant mouse OSM and recombinant human IL6.
  • 经测试应用适用于: ELISA, WB, Neutralisingmore details
  • 种属反应性
    与反应: Human
    不与反应: Mouse
  • 免疫原

    Recombinant full length protein (Human) expressed in E. coli.

  • 阳性对照
    • Tested with human TF-1 cell line.

性能

应用

Our Abpromise guarantee covers the use of ab10842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
Neutralising
  • 应用说明ELISA: Use at a concentration of 0.5-1 µg/ml.
    Neut: ND50 = 0.1 - 5 µg/ml
    WB: Use at a concentration of 1-2 µg/ml. Predicted molecular weight: 22 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
    • 序列相似性Belongs to the LIF/OSM family.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • MGC20461 antibody
      • ONCM_HUMAN antibody
      • Oncostatin M antibody
      • Oncostatin-M antibody
      • OSM antibody
      see all

    Anti-Oncostatin M antibody [17001.31] (ab10842)参考文献

    ab10842 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry regarding product ab10842. Unfortunately there is no information available to indicate that the epitope of this antibody has been mapped. The only information we have is that the immunising protein was recombinant human O...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"