Anti-Oligodendrocyte Specific蛋白抗体- Oligodendrocyte Marker (ab53041)
Key features and details
- Rabbit polyclonal to Oligodendrocyte Specific Protein - Oligodendrocyte Marker
- Suitable for: ICC, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Oligodendrocyte Specific蛋白抗体- Oligodendrocyte Marker
参阅全部 Oligodendrocyte Specific Protein 一抗 -
描述
兔多克隆抗体to Oligodendrocyte Specific蛋白- Oligodendrocyte Marker -
宿主
Rabbit -
特异性
Whilst ab53041 has been generated using synthetic peptide corresponding to human Oligodendrocyte protein (C-terminal), the antibody has only been validated for use in mouse.
Detects endogenous levels of total Oligodendrocyte Specific Protein.
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经测试应用
适用于: ICC, WBmore details -
种属反应性
与反应: Mouse, Rat
预测可用于: Human -
免疫原
Synthetic peptide corresponding to Human Oligodendrocyte Specific Protein (C terminal).
Database link: O75508 -
阳性对照
- WB: Mouse brain extract.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2 -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab53041于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC | (1) |
1/200.
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
|
说明 |
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ICC
1/200. |
WB
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
靶标
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功能
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
序列相似性
Belongs to the claudin family. -
细胞定位
Cell junction > tight junction. Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 5010 Human
- Entrez Gene: 18417 Mouse
- Entrez Gene: 84588 Rat
- Omim: 601326 Human
- SwissProt: O75508 Human
- SwissProt: Q60771 Mouse
- SwissProt: Q99P82 Rat
- Unigene: 31595 Human
see all -
别名
- Claudin 11 antibody
- Claudin-11 antibody
- CLD11_HUMAN antibody
see all
图片
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All lanes : Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker (ab53041) at 1/500 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract with peptide
Predicted band size: 22 kDa
Observed band size: 22 kDaSecondary antibody - anti-rabbit HRP (ab6721)
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (70)
ab53041 被引用在 70 文献中.
- Filiou MD et al. Multi-Omics Analysis Reveals Myelin, Presynaptic and Nicotinate Alterations in the Hippocampus of G72/G30 Transgenic Mice. J Pers Med 12:N/A (2022). PubMed: 35207732
- Gargareta VI et al. Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. Elife 11:N/A (2022). PubMed: 35543322
- Webb SM et al. The incubation of cocaine craving is dissociated from changes in glial cell markers within prefrontal cortex and nucleus accumbens of rats. Addict Neurosci 3:N/A (2022). PubMed: 36034166
- Hosoya M et al. Development of the stria vascularis in the common marmoset, a primate model. Sci Rep 12:19811 (2022). PubMed: 36396805
- Maier-Begandt D et al. A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. Sci Signal 14:N/A (2021). PubMed: 33653920