概述

  • 产品名称Anti-OLFML3抗体
    参阅全部 OLFML3 一抗
  • 描述
    兔多克隆抗体to OLFML3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-228 of Human OLFML3 (AAH09920).

  • 阳性对照
    • A549 and HCT116 whole cell lysates; cal27 xenograft tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab111712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/300. Predicted molecular weight: 46 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. or Tris-EDTA buffer ( PH8.0)

靶标

  • 功能Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
  • 组织特异性Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.
  • 序列相似性Belongs to the OLFML3 family.
    Contains 1 olfactomedin-like domain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HNOEL-iso antibody
    • hOLF44 antibody
    • OLF44 antibody
    • Olfactomedin like 3 antibody
    • Olfactomedin-like protein 3 antibody
    • OLFL3_HUMAN antibody
    • OLFML3 antibody
    see all

Anti-OLFML3 antibody 图像

  • Anti-OLFML3 antibody (ab111712) at 1/3000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 46 kDa
  • ab111712 at 1/500 dilution staining OLFML3 in Formalin-fixed, paraffin-embedded cal27 xenograft tissue by Immunohistochemistry.

Anti-OLFML3 antibody (ab111712)参考文献

ab111712 has not yet been referenced specifically in any publications.

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