Anti-OLFML3抗体(ab102723)

概述

• 产品名称
  Anti-OLFML3抗体
  参阅全部 OLFML3 一抗
• 描述
  兔多克隆抗体to OLFML3
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Mouse, Human
  
• 免疫原

  KLH conjugated synthetic peptide corresponding to a region within internal sequence amino acids 114~143 of Human OLFML3 (Q9NRN5).

• 阳性对照
  • Mouse NIH 3T3 cell line lysates

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
• 存储溶液
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 纯度
  Ammonium Sulphate Precipitation
• 纯化说明
  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Cardiovascular
  • Angiogenesis
  • Adhesion / ECM
  • Extracellular Matrix

  • Signal Transduction
  • Cytoskeleton / ECM
  • Extracellular Matrix
  • ECM Proteins
  • Other ECM Proteins

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • NIH 3T3 whole cell lysate (ab7179)

应用

靶标

• 功能
  Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
• 组织特异性
  Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.
• 序列相似性
  Belongs to the OLFML3 family.
  Contains 1 olfactomedin-like domain.
• 细胞定位
  Secreted.

• Target information above from: UniProt accession Q9NRN5 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 56944 Human
  • Entrez Gene: 99543 Mouse
  • Omim: 610088 Human
  • SwissProt: Q9NRN5 Human
  • SwissProt: Q8BK62 Mouse
  • Unigene: 9315 Human
  • Unigene: 211535 Mouse
• 别名
  • HNOEL-iso antibody
  • hOLF44 antibody
  • OLF44 antibody

  • Olfactomedin like 3 antibody
  • Olfactomedin-like protein 3 antibody
  • OLFL3_HUMAN antibody
  • OLFML3 antibody

  see all

实验方案

• Western blot protocols