Anti-OLFM4抗体(ab105861)
Key features and details
- Rabbit polyclonal to OLFM4
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-OLFM4抗体
参阅全部 OLFM4 一抗 -
描述
兔多克隆抗体to OLFM4 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Dog, Chimpanzee, Monkey -
免疫原
Synthetic peptide corresponding to a region within internal sequence amino acids 400-450 (ASTGNMVISK LNDTTLQVLN TWYTKQYKPS ASNAFMVCGV LYATRTMNTR T) of Human OLFM4, conjugated to KLH.
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阳性对照
- Human liver lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105861于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 57 kDa.
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说明 |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 57 kDa. |
靶标
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功能
An antiapoptotic factor that promotes tumor growth. Promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. Facilitates cell adhesion. -
组织特异性
Expressed during myeloid lineage development. Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone marrow and stomach. Highly expressed in pancreatic cancer tissues and shows an elevated expression level during the early S phase of the cell cycle. Also expressed at high levels in stomach cancer and colon cancer tissues. -
序列相似性
Contains 1 olfactomedin-like domain. -
结构域
The olfactomedin-like domain is involved in the interaction with cadherin. -
翻译后修饰
N-glycosylated. -
细胞定位
Secreted > extracellular space. According to PubMed:15059901, found in mitochondrion and nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 467367 Chimpanzee
- Entrez Gene: 515082 Cow
- Entrez Gene: 485470 Dog
- Entrez Gene: 10562 Human
- Entrez Gene: 380924 Mouse
- Entrez Gene: 290409 Rat
- Omim: 614061 Human
- SwissProt: Q6UX06 Human
see all -
别名
- Antiapoptotic protein GW112 antibody
- bA209J19.1 antibody
- G-CSF-stimulated clone 1 protein antibody
see all
图片
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All lanes : Anti-OLFM4 antibody (ab105861) at 2 µg/ml
Lane 1 : Human liver lysate with no immunizing peptide
Lane 2 : Human liver lysate with immunizing peptide
Predicted band size: 57 kDa -
ab105861, at 5 µg/ml, staining OLFM4 in formalin fixed, paraffin embedded colon tissue by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody followed by alkaline phosphatase-streptavidin and chromogen.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab105861 被引用在 1 文献中.
- Yang C & Gong A Integrated bioinformatics analysis for differentially expressed genes and signaling pathways identification in gastric cancer. Int J Med Sci 18:792-800 (2021). PubMed: 33437215