Anti-OGR1抗体(ab61420)
Key features and details
- Rabbit polyclonal to OGR1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-OGR1抗体
参阅全部 OGR1 一抗 -
描述
兔多克隆抗体to OGR1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Synthetic peptide corresponding to Human OGR1 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
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阳性对照
- Human Testis.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.70
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab61420于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P | (1) |
Use a concentration of 20 µg/ml.
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说明 |
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IHC-P
Use a concentration of 20 µg/ml. |
靶标
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功能
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer. -
组织特异性
Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8111 Human
- Entrez Gene: 238377 Mouse
- Omim: 601404 Human
- SwissProt: Q15743 Human
- SwissProt: Q8BFQ3 Mouse
- Unigene: 8882 Human
- Unigene: 32160 Mouse
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别名
- G protein coupled receptor 68 antibody
- G-protein coupled receptor 68 antibody
- GPR 12A antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab61420 被引用在 2 文献中.
- Herzig M et al. Comprehensive Assessment of GPR68 Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal Antibody. Int J Mol Sci 20:N/A (2019). PubMed: 31652823
- Wiley SZ et al. GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells. FASEB J 32:1170-1183 (2018). PubMed: 29092903