概述

  • 产品名称Anti-OBFC1抗体
    参阅全部 OBFC1 一抗
  • 描述
    小鼠多克隆抗体to OBFC1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human OBFC1 protein (NP_079204.1).

  • 阳性对照
    • Human spleen tissue lysate, HeLa cell lysate and OBFC1 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab89250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.

靶标

  • 功能Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
  • 序列相似性Belongs to the STN1 family.
    Contains 1 OB DNA-binding domain.
  • 细胞定位Nucleus. Chromosome > telomere.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAF 44 antibody
    • AAF44 antibody
    • Alpha accessory factor 44 antibody
    • bA541N10.2 antibody
    • CST complex subunit STN1 antibody
    • FLJ22559 antibody
    • Obfc1 antibody
    • Oligonucleotide/oligosaccharide binding fold containing 1 antibody
    • Oligonucleotide/oligosaccharide-binding fold-containing protein 1 antibody
    • OTTHUMP00000020417 antibody
    • OTTHUMP00000020418 antibody
    • Replication protein A 32 kDa subunit antibody
    • RP11-541N10.2 antibody
    • RPA 32 antibody
    • STN1 antibody
    • STN1_HUMAN antibody
    • Suppressor of cdc thirteen antibody
    • Suppressor of cdc thirteen homolog antibody
    see all

Anti-OBFC1 antibody 图像

  • Anti-OBFC1 antibody (ab89250) at 1 µg/ml + human spleen tissue lysate at 50 µg

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
  • Anti-OBFC1 antibody (ab89250) at 1 µg/ml + HeLa cell lysate at 50 µg

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
  • All lanes : Anti-OBFC1 antibody (ab89250) at 1 µg/ml

    Lane 1 : OBFC1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 42 kDa
    Observed band size : 42 kDa

Anti-OBFC1 antibody (ab89250)参考文献

This product has been referenced in:
  • Stewart JA  et al. Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J 31:3537-49 (2012). Read more (PubMed: 22863775) »

See 1 Publication for this product

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