Anti-OATP2抗体[MDQ] (ab15442)


  • 产品名称Anti-OATP2抗体[MDQ]
    参阅全部 OATP2 一抗
  • 描述
    小鼠单克隆抗体[MDQ] to OATP2
  • 特异性Ab15442 will also cross react with OATP8.
  • 经测试应用适用于: WB, IHC-Fr, ICC/IF, IPmore details
  • 种属反应性
    与反应: Human
    不与反应: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide corresponding to Human OATP2 aa 1-23.


  • 阳性对照
    • Human liver tissue slides.



Our Abpromise guarantee covers the use of ab15442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration.
IHC-Fr 1/20.
ICC/IF 1/20.
IP Use at an assay dependent concentration.


  • 功能Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. May play an important role in the clearance of bile acids and organic anions from the liver.
  • 组织特异性Highly expressed in liver. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.
  • 序列相似性Belongs to the organo anion transporter (TC 2.A.60) family.
    Contains 1 Kazal-like domain.
  • 细胞定位Basolateral cell membrane. Detected in basolateral membranes of hepatocytes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Liver-specific organic anion transporter 1 antibody
    • LST-1 antibody
    • LST1 antibody
    • OATP-2 antibody
    • OATP-C antibody
    • OATP1B1 antibody
    • OATPC antibody
    • SLC21A6 antibody
    • SLCO1B1 antibody
    • SO1B1_HUMAN antibody
    • Sodium-independent organic anion-transporting polypeptide 2 antibody
    • Solute carrier family 21 member 6 antibody
    • Solute carrier organic anion transporter family member 1B1 antibody
    see all

Anti-OATP2 antibody [MDQ] 图像

  • Immunocytochemistry/Immunofluorescence analysis of HepG2 cells labeling OATP2 (green) with ab15542 at 1/20. F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue). Cells were fixed with formaldehyde and incubated with the primary antibody overnight at 4°C. A DyLight 488-conjugated secondary antibody was used. 60X magnification. Right - negative control.

Anti-OATP2 antibody [MDQ] (ab15442)参考文献

ab15442 has not yet been referenced specifically in any publications.

Product Wall

Any products that require an MSDS form will have a link on the product's online datasheet to the data. It will be a PDF document link labeled 'SDS'. Please see attached image for example of what to look for on the datasheet. If no 'SDS' link ...

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Application Western blot
Sample Human Cell lysate - whole cell (human HEK293 cells over-expressing)
Loading amount 150 µg
Specification human HEK293 cells over-expressing
Gel Running Conditions Reduced Denaturing (denature at 70C for 10mins, 7.5% gel)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C

Abcam user community

Verified customer

提交于 Sep 08 2011

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - other (transiently transfected HeLa cells)
Loading amount 100000 cells
Specification transiently transfected HeLa cells
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%

Abcam user community

Verified customer

提交于 Dec 19 2006

Thank you for your enquiry. I am sorry to hear that you have been having difficulties with this antibody. I have read through your technical questionaire and I have a few comments. OATP2 antibody [MDQ] (ab15442) has been tested for its applicat...

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Thank you for your enquiry. Both antibodies were tested in IP using human liver samples (~20-50 ug) and about 1 ug/ml of antibody used. For IF, human liver and transfected HEK293 whole cell lysates were used. Ab15442 was used at a dilution of 1:20. The...

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Thank you for bringing this to our attention. The immunogen sequence is from OATP2, however this product will also recognise OATP8. The data sheet has now been updated to reflect this. Please let me know if you spot any further problems. I apologize fo...

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