概述

  • 产品名称Anti-NYREN18抗体
    参阅全部 NYREN18 一抗
  • 描述
    兔多克隆抗体to NYREN18
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH selected within aa 100~125 of human NYREN18.

  • 阳性对照
    • Mouse liver lysate. Human hepatocarcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明This antibody is purified through a protein G column, eluted out with both high and low pH buffers, neutralized immediately after elution then followed by dialysis against PBS.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab38438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
  • 组织特异性Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
  • 序列相似性Contains 3 UBA domains.
  • 细胞定位Nucleus. Predominantly nuclear.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BS4 antibody
    • NEDD8 ultimate buster 1 antibody
    • Negative regulator of ubiquitin like proteins 1 antibody
    • Negative regulator of ubiquitin-like proteins 1 antibody
    • NUB1 antibody
    • NUB1_HUMAN antibody
    • NUB1L antibody
    • NY REN 18 antibody
    • NYREN18 antibody
    • Renal carcinoma antigen NY-REN-18 antibody
    see all

Anti-NYREN18 antibody 图像

  • Anti-NYREN18 antibody (ab38438) at 1/100 dilution + Mouse liver lysate

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : 14 kDa,23 kDa,30 kDa,45 kDa. We are unsure as to the identity of these extra bands.
  • Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ab38438, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining

Anti-NYREN18 antibody (ab38438)参考文献

ab38438 has not yet been referenced specifically in any publications.

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