概述

  • 产品名称Anti-NXF3抗体
    参阅全部 NXF3 一抗
  • 描述
    小鼠单克隆抗体to NXF3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human, Recombinant Fragment
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-532 of Human NXF3 (AAH31616) with a proprietary tag.

  • 阳性对照
    • Recombinant Protein. Human kidney tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab118337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 60 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein in western blotting.
IHC-P Use a concentration of 5 µg/ml. Antigen retrieval is not essential but may optimise staining. Place sample in 1X citrate buffer (pH 6.0) in pressure cooker under 125 °C for 4min and under 90 °C for 45min, cool sample subsequently.

靶标

  • 功能May function as a tissue-specific nuclear mRNA export factor.
  • 组织特异性Expressed at high level in testis and at low level in a small number of tissues.
  • 序列相似性Belongs to the NXF family.
    Contains 1 NTF2 domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • 结构域Lacks C-terminal domain that mediates direct interactions with nucleoporins.
    Contains a novel CRM1-dependent nuclear export signal that compensates in cis for the loss of the nuclear pore targeting domain.
    The RNA-binding domain is a non-canonical RNP-type domain.
  • 细胞定位Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Nuclear RNA export factor 3 antibody
    • NXF3 antibody
    • NXF3_HUMAN antibody
    • OTTHUMP00000023726 antibody
    • OTTHUMP00000023727 antibody
    • TAP like protein 3 antibody
    • TAP-like protein 3 antibody
    • TAPL 3 antibody
    • TAPL-3 antibody
    • TAPL3 antibody
    see all

Anti-NXF3 antibody 图像

  • Anti-NXF3 antibody (ab118337) at 5 µg/ml + Recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 60 kDa
  • ab118337 at 5 µg/ml staining NXF3 in Formalin-Fixed, Paraffin-Embedded Human Kidney tissue by Immunohistochemistry.

Anti-NXF3 antibody (ab118337)参考文献

ab118337 has not yet been referenced specifically in any publications.

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