概述

  • 产品名称Anti-NUT抗体
    参阅全部 NUT 一抗
  • 描述
    兔多克隆抗体to NUT
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: TCPLNVHSYDPQGEGRVDPDLSKPKNLAPLQESQESYTTGTPKATSSHQG LGSTLPRRGT RNAIVPRETSVSKTHRSA, corresponding to amino acids 920-997 of Human NUT (Q86Y26).

  • 阳性对照
    • Human testis tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab122649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 组织特异性Specifically expressed in testis.
  • 疾病相关Note=A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.
    Note=A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.
  • 序列相似性Belongs to the FAM22 family.
  • 翻译后修饰Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.
  • 细胞定位Cytoplasm. Nucleus. Shuttles between nucleus and cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C15orf55 antibody
    • Chromosome 15 open reading frame 55 antibody
    • DKFZp434O192 antibody
    • MGC138683 antibody
    • MGC138684 antibody
    • Nuclear protein in testis antibody
    • NUT antibody
    • NUT_HUMAN antibody
    • Protein NUT antibody
    see all

Anti-NUT antibody 图像

  • ab122649, at 1/500, staining NUT in paraffin embedded Human testis tissue by Immunohistochemistry.

Anti-NUT antibody (ab122649)参考文献

ab122649 has not yet been referenced specifically in any publications.

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