概述

  • 产品名称Anti-Nurim抗体
  • 描述
    兔多克隆抗体to Nurim
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Dog, Human, Pig, Chimpanzee, Macaque Monkey
  • 免疫原

    Synthetic peptide, derived from amino acids 200-250 of Human Nurim.

  • 阳性对照
    • HeLa cfell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 0.05% BSA, PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab22151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).

靶标

  • 相关性Nurim is an inner nuclear membrane (INM) protein that was first isolated in a visual screen for nuclear envelope-localizing proteins. Nurim lacks an N-terminal domain characteristic of other INM proteins examined to date and may represent a class of proteins that localize to the INM by a distinct mechanism. It is indicated that Nurim is a six transmembrane-spanning protein and contains a hairpin turn in its C-terminal transmembrane domain, resulting in the N and C termini residing on the same side of the membrane. A loop region between the fourth and fifth transmembrane domains is exposed toward the nucleoplasm and contains a region accessible for site-specific endoproteinase cleavage. In biochemical fractionation, Nurim remained extremely tightly bound to nuclear fractions. Under conditions in which nuclear lamins were completely extracted, a significant population of nurim remained resistant to solubilization. This tight binding requires the C-terminal region of the protein. Consideration of sequence alignments and identification of specific topological features of Nurim indicate that it may possess enzymatic function.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • NRM antibody
    • Nuclear envelope membrane protein antibody

Anti-Nurim antibody 图像

  • Anti-Nurim antibody (ab22151) at 2 µg/ml + HeLa cell lysate

    Predicted band size : 29 kDa
    Observed band size : 29 kDa

Anti-Nurim antibody (ab22151)参考文献

ab22151 has not yet been referenced specifically in any publications.

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