概述

  • 产品名称Anti-NUP50抗体
    参阅全部 NUP50 一抗
  • 描述
    小鼠多克隆抗体to NUP50
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human NUP50 (NP_009103.2, amino acids 1-468)

  • 阳性对照
    • Human liver tissue lysate, NUP50 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab89524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.

靶标

  • 功能Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
  • 组织特异性Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
  • 序列相似性Contains 1 RanBD1 domain.
  • 结构域Contains FG repeats.
  • 细胞定位Nucleus > nuclear pore complex. Nucleus membrane. Localizes to the nucleoplasmic fibrils of the nuclear pore complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 50 kDa nucleoporin antibody
    • NPAP60 antibody
    • NPAP60L antibody
    • Nuclear pore associated protein 60L antibody
    • Nuclear pore complex protein Nup50 antibody
    • Nuclear pore-associated protein 60 kDa-like antibody
    • Nucleoporin 50 antibody
    • Nucleoporin 50kDa antibody
    • Nucleoporin Nup50 antibody
    • Nup50 antibody
    • NUP50_HUMAN antibody
    • PRO1146 antibody
    see all

Anti-NUP50 antibody 图像

  • Anti-NUP50 antibody (ab89524) at 1 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 50 kDa
    Observed band size : 50 kDa
    Additional bands at : 32 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-NUP50 antibody (ab89524) at 1 µg/ml

    Lane 1 : NUP50 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 50 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

Anti-NUP50 antibody (ab89524)参考文献

ab89524 has not yet been referenced specifically in any publications.

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