Anti-NUDC抗体[EPR5072] (ab109370)


  • 产品名称Anti-NUDC抗体[EPR5072]
    参阅全部 NUDC 一抗
  • 描述
    兔单克隆抗体[EPR5072] to NUDC
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
    不适用于: ICC or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human TRPV6.

  • 阳性对照
    • HepG2, 293T, HeLa, and SH-SY5Y cell lysates; Human kidney and placenta tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.



Our Abpromise guarantee covers the use of ab109370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 83 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC or IP.
  • 靶标

    • 功能Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
    • 组织特异性Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
    • 序列相似性Belongs to the nudC family.
      Contains 1 CS domain.
    • 翻译后修饰Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.
    • 细胞定位Cytoplasm > cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HNUDC antibody
      • MNUDC antibody
      • MNUDC protein antibody
      • NPD011 antibody
      • Nuclear distribution C homolog antibody
      • Nuclear distribution gene C (A.nidulans) homolog antibody
      • Nuclear distribution gene C homolog antibody
      • Nuclear distribution gene C homolog (A. nidulans) antibody
      • Nuclear distribution protein C homolog antibody
      • Nuclear migration protein nudC antibody
      • nudC antibody
      • NudC nuclear distribution protein antibody
      • NUDC_HUMAN antibody
      • OTTHUMP00000004405 antibody
      • SIG 92 antibody
      • SIG92 antibody
      see all

    Anti-NUDC antibody [EPR5072] 图像

    • All lanes : Anti-NUDC antibody [EPR5072] (ab109370) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : SH-SY5Y cell lysate

      Lysates/proteins at 10 µg per lane.

      HRP labelled Goat anti-Rabbit at 1/2000 dilution

      Predicted band size : 83 kDa
    • Immunohistochemical analysis of paraffin-embedded Human kidney tissue using ab109370 at 1/100 dilution.
    • Immunohistochemical analysis of paraffin-embedded Human placenta tissue using ab109370 at 1/100 dilution.

    Anti-NUDC antibody [EPR5072] (ab109370)参考文献

    ab109370 has not yet been referenced specifically in any publications.

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