概述

  • 产品名称Anti-NUDC抗体
    参阅全部 NUDC 一抗
  • 描述
    小鼠单克隆抗体to NUDC
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-332 of Human NUDC

性能

应用

Our Abpromise guarantee covers the use of ab56999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
    • 组织特异性Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
    • 序列相似性Belongs to the nudC family.
      Contains 1 CS domain.
    • 翻译后修饰Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.
    • 细胞定位Cytoplasm > cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HNUDC antibody
      • MNUDC antibody
      • MNUDC protein antibody
      • NPD011 antibody
      • Nuclear distribution C homolog antibody
      • Nuclear distribution gene C (A.nidulans) homolog antibody
      • Nuclear distribution gene C homolog antibody
      • Nuclear distribution gene C homolog (A. nidulans) antibody
      • Nuclear distribution protein C homolog antibody
      • Nuclear migration protein nudC antibody
      • nudC antibody
      • NudC nuclear distribution protein antibody
      • NUDC_HUMAN antibody
      • OTTHUMP00000004405 antibody
      • SIG 92 antibody
      • SIG92 antibody
      see all

    Anti-NUDC antibody 图像



    • Predicted band size : 38 kDa
      NUDC antibody (ab56999) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-NUDC antibody (ab56999)参考文献

    ab56999 has not yet been referenced specifically in any publications.

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