概述

  • 产品名称Anti-NUDC抗体
    参阅全部 NUDC 一抗
  • 描述
    山羊多克隆抗体to NUDC
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Zebrafish
  • 免疫原

    Synthetic peptide:

    C-PNLGNGADLPNYR

    , corresponding to internal sequence amino acids 161-173 of Human NUDC (NP_006591.1)

  • 阳性对照
    • HeLa cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab106935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 38 kDa).

靶标

  • 功能Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
  • 组织特异性Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
  • 序列相似性Belongs to the nudC family.
    Contains 1 CS domain.
  • 翻译后修饰Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.
  • 细胞定位Cytoplasm > cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HNUDC antibody
    • MNUDC antibody
    • MNUDC protein antibody
    • NPD011 antibody
    • Nuclear distribution C homolog antibody
    • Nuclear distribution gene C (A.nidulans) homolog antibody
    • Nuclear distribution gene C homolog antibody
    • Nuclear distribution gene C homolog (A. nidulans) antibody
    • Nuclear distribution protein C homolog antibody
    • Nuclear migration protein nudC antibody
    • nudC antibody
    • NudC nuclear distribution protein antibody
    • NUDC_HUMAN antibody
    • OTTHUMP00000004405 antibody
    • SIG 92 antibody
    • SIG92 antibody
    see all

Anti-NUDC antibody 图像

Anti-NUDC antibody (ab106935)参考文献

ab106935 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106935.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"