Anti-Nucleus and Mitotic Cell Antigen抗体[2Q2257] (ab64608)

概述

  • 产品名称Anti-Nucleus and Mitotic Cell Antigen抗体[2Q2257]
  • 描述
    小鼠单克隆抗体[2Q2257] to Nucleus and Mitotic Cell Antigen
  • 特异性ab64608 reacts with the cell nucleus and mitotic cell antigen (poles of the mitotic spindle and adjacent micotubules, centrosomes). It is possibly related to the NuMA protein. By Western blot this antibody recognizes a major band at 210kD, preferentially in mitotic cells (additional weaker bands at 240 and 180kD).
  • 经测试应用适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Live Ls 174T cells (colonic carcinoma).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Purified IgM
  • 克隆单克隆
  • 克隆编号2Q2257
  • 同种型IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab64608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Detects a band of approximately 210 kDa.
IHC-Fr Use at an assay dependent dilution.

靶标

  • 相关性The life cycle of a eukaryotic cell consists of various phases, two of which can easily be identified. Firstly, during mitosis (M-phase), in which the cell divides into two identical daughter cells, chromosome condensation and spindle formation are microscopically visible. Secondly, in S-phase the DNA of a cell is replicated, a process that can be detected using biochemical techniques. In between the M and S phase two gap phases occur: the G1-phase, the gap between mitosis and the start of DNA replication, and G2-phase, the gap between completion of DNA replication and the onset of mitosis. From G1-phase a cell can leave the cell cycle and enter G0, a ‘quiescent’ phase. Regulation of the cell cycle predominantly occurs at three major control points, which govern the transition from G0 to G1, from G1 to S and from G2 to M-phase. The Nucleus and Mitotic Cell Antigen is an antigen detected at the poles of the mitotic spindle and adjacent micotubules and centrosomes.

Anti-Nucleus and Mitotic Cell Antigen antibody [2Q2257] (ab64608)参考文献

ab64608 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab64608.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"