概述

  • 产品名称Anti-Nucleoporin p62抗体[RL31]
    参阅全部 Nucleoporin p62 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[RL31] to Nucleoporin p62
  • 特异性Detects the nucleoporin p62 O-linked glycoprotein in the p62 complex from rat tissues.
  • 经测试应用适用于: ICC/IF, IP, IHC-Fr, WBmore details
  • 种属反应性
    与反应: Rat, Human, Non Human Primates, Amphibians
  • 免疫原

    Other Immunogen Type corresponding to Nucleoporin p62. Equivalent to O-linked glycoprotein-enriched fraction from rat liver nuclear envelope

  • 阳性对照
    • Rat liver nuclear envelope fractions.

性能

应用

Our Abpromise guarantee covers the use of ab2736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/50.

This antibody stains both the nucleoplasmic and cytoplasmic surfaces of rat's liver Nup62.

IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB 1/200. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa).

This antibody detects a single 62 kDa band in rat liver nuclear envelope fractions.

靶标

  • 相关性The nuclear pore complex is a structure that extends across the nuclear envelope and regulates the flow of macromolecules between the cytoplasm and the nucleus. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. Nup 62 is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. There are multiple transcript variants of this gene, however, they encode a single protein isoform. This protein undergoes post-translational modifications. It contains about 10 N-acetylglucosamine side chain sites.
  • 细胞定位Nucleus; nuclear pore complex. Cytoplasm; cytoskeleton; spindle pole. Note: Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.
  • 数据库链接
  • 别名
    • 62 kDa nucleoporin antibody
    • DKFZp547L134 antibody
    • FLJ20822 antibody
    • FLJ43869 antibody
    • IBSN antibody
    • MGC841 antibody
    • Nuclear pore glycoprotein p62 antibody
    • nucleoporin 62kDa antibody
    • Nucleoporin Nup62 antibody
    • nucleoporin p62 antibody
    • nucleoporin p62KD antibody
    • NUP62 antibody
    • NUP62 protein antibody
    • p62 antibody
    • SNDI antibody
    see all

Anti-Nucleoporin p62 antibody [RL31] (ab2736)参考文献

This product has been referenced in:
  • Guan T  et al. Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Mol Biol Cell 6:1591-603 (1995). Read more (PubMed: 8589458) »

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