Anti-Nucleobindin 1抗体(ab23387)

概述

  • 产品名称Anti-Nucleobindin 1抗体
    参阅全部 Nucleobindin 1 一抗
  • 描述
    兔多克隆抗体to Nucleobindin 1
  • 经测试应用适用于: ICC/IFmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse
  • 免疫原

    A region within synthetic peptide: SQPDGQLQFR ADTGDAPVPA PAGDQKDVPA SEKKVPEQPP VLPQLDSQHL conjugated to KLH, corresponding to C terminal amino acids 410-459 of Rat Nucleobindin 1

  • 阳性对照
    • NRK cells
  • 常规说明


    ab23387 is also useful as a Golgi marker in immunohistochemistry.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • Primary antibody说明ab23387 is also useful as a Golgi marker in immunohistochemistry.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis.
  • 组织特异性Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas.
  • 序列相似性Belongs to the nucleobindin family.
    Contains 2 EF-hand domains.
  • 结构域The EF-hand domains are unfolded in the absence of Ca(2+) and fold upon Ca(2+) addition.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Golgi apparatus > cis-Golgi network membrane. Cytoplasm. A small fraction of the protein may be cytoplasmic.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CALNUC antibody
    • FLJ40471 antibody
    • NUC antibody
    • NUCB 1 antibody
    • NUCB1 antibody
    • NUCB1_HUMAN antibody
    • Nucleobindin 1 antibody
    • Nucleobindin-1 antibody
    see all

Anti-Nucleobindin 1 antibody 图像

  • Golgi of NRK cells are detected with Nucleobindin 1 antibody ab23387 (green) at 4-8µg/ml. Nuclei (blue) were stained with DAPI.

Anti-Nucleobindin 1 antibody (ab23387)参考文献

ab23387 has not yet been referenced specifically in any publications.

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