Anti-NUAK2抗体- Aminoterminal end (ab71398)

概述

  • 产品名称Anti-NUAK2抗体- Aminoterminal end
    参阅全部 NUAK2 一抗
  • 描述
    兔多克隆抗体to NUAK2 - Aminoterminal end
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N-terminal region of human NUAK2.

  • 阳性对照
    • Transfected/ non-transfected 293 cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab71398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 80 kDa (predicted molecular weight: 70 kDa).
ELISA 1/1000.

靶标

  • 功能Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated at Thr-208 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Autophosphorylated in vitro.
  • Information by UniProt
  • 数据库链接
  • 形式Involved in actin cytoskeleton organization.
  • 别名
    • DKFZp434J037 antibody
    • DKFZp686F01113 antibody
    • FLJ90349 antibody
    • NUAK family SNF1 like kinase 2 antibody
    • NUAK family SNF1-like kinase 2 antibody
    • Nuak2 antibody
    • NUAK2_HUMAN antibody
    • Omphalocele kinase 2 antibody
    • SNARK antibody
    • SNF1/AMP activated protein kinase antibody
    • SNF1/AMP kinase related kinase antibody
    • SNF1/AMP kinase-related kinase antibody
    see all

Anti-NUAK2 antibody - Aminoterminal end 图像

  • All lanes : Anti-NUAK2 antibody - Aminoterminal end (ab71398) at 1/50 dilution

    Lane 1 : Non-transfected 293 cell line lysates
    Lane 2 : NUAK2 transfected 293 cell line lysates

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 70 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)

Anti-NUAK2 antibody - Aminoterminal end (ab71398)参考文献

ab71398 has not yet been referenced specifically in any publications.

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