Anti-NUAK2抗体(ab107287)

概述

• 产品名称
  Anti-NUAK2抗体
  参阅全部 NUAK2 一抗
• 描述
  兔多克隆抗体to NUAK2
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Mouse, Human
  
• 免疫原

  Recombinant protein from Human NUAK2 (NP_112214.1).

• 阳性对照
  • NIH 3T3 cell lysate, NCI-H292 cell lysate

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
• 存储溶液
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 纯化说明
  Purified through a protein A column, followed by peptide affinity purification.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Signal Transduction
  • Cytoskeleton / ECM
  • Cytoskeleton
  • Microfilaments
  • Actin etc
  • Actin

  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • Other Kinases

  • Cancer
  • Invasion/microenvironment
  • Apoptosis
  • Other

  • Cancer
  • Cell Death
  • Apoptosis
  • Other

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能
  Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
• 序列相似性
  Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
  Contains 1 protein kinase domain.
• 翻译后修饰
  Phosphorylated at Thr-208 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Autophosphorylated in vitro.

• Target information above from: UniProt accession Q9H093 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 81788 Human
  • Entrez Gene: 74137 Mouse
  • Omim: 608131 Human
  • SwissProt: Q9H093 Human
  • SwissProt: Q8BZN4 Mouse
  • Unigene: 497512 Human
  • Unigene: 100666 Mouse
• 形式
  Involved in actin cytoskeleton organization.
• 别名
  • DKFZp434J037 antibody
  • DKFZp686F01113 antibody
  • FLJ90349 antibody

  • NUAK family SNF1 like kinase 2 antibody
  • NUAK family SNF1-like kinase 2 antibody
  • Nuak2 antibody
  • NUAK2_HUMAN antibody
  • Omphalocele kinase 2 antibody
  • SNARK antibody
  • SNF1/AMP activated protein kinase antibody
  • SNF1/AMP kinase related kinase antibody
  • SNF1/AMP kinase-related kinase antibody

  see all

实验方案

• Western blot protocols