Anti-NTH1抗体(ab93)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to NTH1
  • 特异性
    This antibody is specific for NTH1.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    CANRLWTKKATKSPE

    with a cysteine added for conjugation to KLH, corresponding to amino acids 237-249 of Human NTH1.

  • 阳性对照
    • K562 cell extracts , Hela cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab93 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Predicted molecular weight: 37 kDa.

靶标

  • 功能
    Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.
  • 组织特异性
    Widely expressed with highest levels in heart and lowest levels in lung and liver.
  • 序列相似性
    Belongs to the Nth/MutY family.
  • 发展阶段
    Expression levels are regulated during the cell cycle with increased levels during early and mid S-phase.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bifunctional DNA N glycoslyase/DNA (apurinic or apyrimidinic site) lyase antibody
    • DNA glycoslyase/AP lyase antibody
    • Endonuclease III like protein 1 antibody
    • Endonuclease III-like protein 1 antibody
    • hNTH1 antibody
    • NTH 1 antibody
    • nth endonuclease III like 1 (E. coli) antibody
    • NTH endonuclease III Like 1 antibody
    • NTH1 antibody
    • NTHL 1 antibody
    • Nthl1 antibody
    • NTHL1_HUMAN antibody
    • OCTS 3 antibody
    • OCTS3 antibody
    see all

实验方案

文献

ab93 has not yet been referenced specifically in any publications.

客户评价及客户问答

We do not have any details on immunohistochemistry with this antibody. My guess is that it does not work well for that application as we have supporting IH data for the MTH1 and hOgg1 antibodies but nothing for the NTH1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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