Anti-NT5C2抗体(ab96084)
Key features and details
- Rabbit polyclonal to NT5C2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-NT5C2抗体 -
描述
兔多克隆抗体to NT5C2 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Cow, Zebrafish -
免疫原
Recombinant fragment, containing a sequence corresponding to a region within amino acids 108 and 332 of Human NT5C2.
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阳性对照
- HepG2 whole cell lysate (ab7900) can be used as a positive control in WB. H1299 and HeLaS3 whole cell lysate, OVCA tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96084于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 65 kDa.
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IHC-P |
1/100 - 1/250.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 65 kDa. |
IHC-P
1/100 - 1/250. |
靶标
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功能
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides. -
序列相似性
Belongs to the 5'(3')-deoxyribonucleotidase family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 281951 Cow
- Entrez Gene: 22978 Human
- Entrez Gene: 76952 Mouse
- Entrez Gene: 324845 Zebrafish
- Omim: 600417 Human
- SwissProt: O46411 Cow
- SwissProt: P49902 Human
- SwissProt: Q3V1L4 Mouse
see all -
别名
- 5' nucleotidase (purine) cytosolic type B antibody
- 5NTC_HUMAN antibody
- cN II antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab96084 被引用在 4 文献中.
- Fei X et al. TRIM22 orchestrates the proliferation of GBMs and the benefits of TMZ by coordinating the modification and degradation of RIG-I. Mol Ther Oncolytics 26:413-428 (2022). PubMed: 36159777
- Carlini F et al. Different Susceptibility of T and B Cells to Cladribine Depends On Their Levels of Deoxycytidine Kinase Activity Linked to Activation Status. J Neuroimmune Pharmacol N/A:N/A (2021). PubMed: 33851318
- Tzoneva G et al. Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. Nat Med 19:368-71 (2013). WB . PubMed: 23377281
- Meyer JA et al. Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia. Nat Genet 45:290-4 (2013). PubMed: 23377183