概述

  • 产品名称Anti-NT5C2抗体
    参阅全部 NT5C2 一抗
  • 描述
    小鼠单克隆抗体to NT5C2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-562 of Human NT5C2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

靶标

  • 功能May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
  • 序列相似性Belongs to the 5'(3')-deoxyribonucleotidase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5' nucleotidase (purine) cytosolic type B antibody
    • 5NTC_HUMAN antibody
    • cN II antibody
    • Cytosolic 5''-nucleotidase II antibody
    • Cytosolic IMP/GMP-specific 5'-nucleotidase antibody
    • Cytosolic purine 5' nucleotidase antibody
    • Cytosolic purine 5''-nucleotidase antibody
    • GMP antibody
    • NT5B antibody
    • nt5c2 antibody
    • NT5CP antibody
    • NUCLEOTIDASE, 5-PRIME, CYTOSOLIC II antibody
    • NUCLEOTIDASE, 5-PRIME, TYPE B antibody
    • PNT5 antibody
    • PURINE 5-PRIME-NUCLEOTIDASE antibody
    see all

Anti-NT5C2 antibody 图像

  • Western blot against tagged recombinant protein immunogen using ab56938 NT5C2 antibody at 1ug/ml. Predicted band size of immunogen is 88 kDa

Anti-NT5C2 antibody (ab56938)参考文献

This product has been referenced in:
  • Mitra AK  et al. Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. J Pharmacol Exp Ther 339:9-23 (2011). WB ; Human . Read more (PubMed: 21712425) »

See 1 Publication for this product

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