Anti-NSE抗体[NSE 224 (5E2)] (ab115955)

概述

  • 产品名称Anti-NSE抗体[NSE 224 (5E2)]
    参阅全部 NSE 一抗
  • 描述
    小鼠单克隆抗体[NSE 224 (5E2)] to NSE
  • 特异性This clone reacts with 47 kDa component of gamma Enolase isozyme.
  • 经测试应用适用于: IHC-P, IHC-Fr, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified Human NSE protein.

  • 阳性对照
    • Human brain, pancreas or small intestine tissues.
  • 常规说明


    This clone reacts with NSE found primarily in neurons, neuroendocrine cell, striated and smooth muscle cells, megakaryocytes, T cells and some platelets. In neoplastic tissues, the antibody reacts with gangliomas, oat cell carcinoma, astrocytomas, paraganglomas, glioblastomas, pheochromocytomas, melanomas and schwannoma.

性能

应用

Our Abpromise guarantee covers the use of ab115955 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
IHC-Fr 1/50 - 1/100.
ICC Use at an assay dependent concentration.

靶标

  • 功能Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
  • 组织特异性The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
  • 通路Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
  • 序列相似性Belongs to the enolase family.
  • 发展阶段During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.
  • 细胞定位Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2 phospho D glycerate hydrolyase antibody
    • 2-phospho-D-glycerate hydro-lyase antibody
    • Eno 2 antibody
    • ENO2 antibody
    • ENOG antibody
    • ENOG_HUMAN antibody
    • Enolase 2 (gamma, neuronal) antibody
    • Enolase 2 antibody
    • Enolase 2 gamma neuronal antibody
    • Enolase2 antibody
    • Epididymis secretory protein Li 279 antibody
    • Gamma enolase antibody
    • Gamma-enolase antibody
    • HEL S 279 antibody
    • Neural enolase antibody
    • Neuron specific enolase antibody
    • Neuron specific gamma enolase antibody
    • Neuron-specific enolase antibody
    • Neurone specific enolase antibody
    • NSE antibody
    see all

Anti-NSE antibody [NSE 224 (5E2)] (ab115955)参考文献

ab115955 has not yet been referenced specifically in any publications.

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