Anti-NSE抗体- Neuronal Marker (ab834)

概述

  • 产品名称Anti-NSE抗体- Neuronal Marker
    参阅全部 NSE 一抗
  • 描述
    兔多克隆抗体to NSE - Neuronal Marker
  • 特异性This antibody reacts with human isoenzymes of neuron specific enolase containing gamma subunits. This antibody gives a specific staining in neurons of the brain, in islets of langerhans in pancreas and in peripheral nerves of the skin. No staining with other tissue types has been seen.
  • 经测试应用适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Cow, Human
  • 免疫原

    Neuron specific enolase (gamma-gamma isoenzyme) isolated from bovine brain.

性能

应用

Our Abpromise guarantee covers the use of ab834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
  • 应用说明IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method.
    Staining Protocol: We suggest an incubation period of 30-60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
  • 靶标

    • 功能Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
    • 组织特异性The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
    • 通路Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
    • 序列相似性Belongs to the enolase family.
    • 发展阶段During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.
    • 细胞定位Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 2 phospho D glycerate hydrolyase antibody
      • 2-phospho-D-glycerate hydro-lyase antibody
      • Eno 2 antibody
      • ENO2 antibody
      • ENOG antibody
      • ENOG_HUMAN antibody
      • Enolase 2 (gamma, neuronal) antibody
      • Enolase 2 antibody
      • Enolase 2 gamma neuronal antibody
      • Enolase2 antibody
      • Epididymis secretory protein Li 279 antibody
      • Gamma enolase antibody
      • Gamma-enolase antibody
      • HEL S 279 antibody
      • Neural enolase antibody
      • Neuron specific enolase antibody
      • Neuron specific gamma enolase antibody
      • Neuron-specific enolase antibody
      • Neurone specific enolase antibody
      • NSE antibody
      see all

    Anti-NSE antibody - Neuronal Marker 图像

    • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue, staining NSE - Neuronal Marker with ab834.

    Anti-NSE antibody - Neuronal Marker (ab834)参考文献

    ab834 has not yet been referenced specifically in any publications.

    Product Wall

    We recommend the use of 0.025% Triton in the TBS as it helps to reduce surface tension, allowing reagents to cover the whole tissue section with ease. It is also believed to dissolve Fc receptors, therefore reducing non-specific binding. Furthermore, T...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"