概述

  • 产品名称Anti-NSDHL抗体
    参阅全部 NSDHL 一抗
  • 描述
    小鼠多克隆抗体to NSDHL
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human NSDHL protein (NP_057006.1)

  • 阳性对照
    • Human liver tissue lysate, NSDHL transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab92904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Predicted molecular weight: 42 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 组织特异性Brain, heart, liver, lung, kidney, skin and placenta.
    • 通路Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6.
    • 疾病相关Defects in NSDHL are the cause of congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) [MIM:308050]. CHILD is an X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, which typically results in male lethality. Clinically, it is characterized by congenital, unilateral, ichthyosisform erythroderma with striking lateralization, sharp midline demarcation, and ipsilateral limb defects and hypoplasia of the body. Limbs defects range from hypoplasia of digits or ribs to complete amelia, often including scoliosis.
      Defects in NSDHL are the cause of CK syndrome (CKS) [MIM:300831]. CKS is a disorder characterized by mild to severe cognitive impairment, seizures, microcephaly, cerebral cortical malformations, dysmorphic facial features, and thin body habitus.
    • 序列相似性Belongs to the 3-beta-HSD family.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • decarboxylating antibody
      • H105E3 antibody
      • H105e3 protein antibody
      • NAD(P) dependent steroid dehydrogenase like antibody
      • NSDHL antibody
      • NSDHL_HUMAN antibody
      • Protein H105e3 antibody
      • SDR31E1 antibody
      • Short chain dehydrogenase/reductase family 31E member 1 antibody
      • Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating antibody
      • Sterol-4-alpha-carboxylate 3-dehydrogenase antibody
      • XAP104 antibody
      see all

    Anti-NSDHL antibody 图像

    • Anti-NSDHL antibody (ab92904) at 1/500 dilution + Human liver tissue lysate at 50 µg

      Predicted band size : 42 kDa
    • All lanes : Anti-NSDHL antibody (ab92904) at 1/500 dilution

      Lane 1 : NSDHL transfected 293T cell lysate
      Lane 2 : Untransfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 42 kDa

    Anti-NSDHL antibody (ab92904)参考文献

    ab92904 has not yet been referenced specifically in any publications.

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