概述

  • 产品名称Anti-NSDHL抗体
    参阅全部 NSDHL 一抗
  • 描述
    兔多克隆抗体to NSDHL
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant full length Human protein NSDHL (NP_057006.1)

  • 阳性对照
    • Mouse lung tissue, A431 cell line and NSDHL transfected 293T cell lysates

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab102805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 42 kDa.

靶标

  • 组织特异性Brain, heart, liver, lung, kidney, skin and placenta.
  • 通路Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6.
  • 疾病相关Defects in NSDHL are the cause of congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) [MIM:308050]. CHILD is an X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, which typically results in male lethality. Clinically, it is characterized by congenital, unilateral, ichthyosisform erythroderma with striking lateralization, sharp midline demarcation, and ipsilateral limb defects and hypoplasia of the body. Limbs defects range from hypoplasia of digits or ribs to complete amelia, often including scoliosis.
    Defects in NSDHL are the cause of CK syndrome (CKS) [MIM:300831]. CKS is a disorder characterized by mild to severe cognitive impairment, seizures, microcephaly, cerebral cortical malformations, dysmorphic facial features, and thin body habitus.
  • 序列相似性Belongs to the 3-beta-HSD family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • decarboxylating antibody
    • H105E3 antibody
    • H105e3 protein antibody
    • NAD(P) dependent steroid dehydrogenase like antibody
    • NSDHL antibody
    • NSDHL_HUMAN antibody
    • Protein H105e3 antibody
    • SDR31E1 antibody
    • Short chain dehydrogenase/reductase family 31E member 1 antibody
    • Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating antibody
    • Sterol-4-alpha-carboxylate 3-dehydrogenase antibody
    • XAP104 antibody
    see all

Anti-NSDHL antibody 图像

  • Anti-NSDHL antibody (ab102805) at 5 µg/ml + Mouse lung tissue lysate at 50 µg

    Secondary
    Goat anti-Mouse IgG HRP at 1/2500 dilution

    Predicted band size : 42 kDa
  • Anti-NSDHL antibody (ab102805) at 5 µg/ml + A431 cell lysate at 50 µg

    Predicted band size : 42 kDa
  • All lanes : Anti-NSDHL antibody (ab102805) at 5 µg/ml

    Lane 1 : NSDHL transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 42 kDa

Anti-NSDHL antibody (ab102805)参考文献

ab102805 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab102805.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"