Synthetic peptide (Human)
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 22420896
Use a concentration of 1 µg/ml. Detects a band of approximately 32 kDa (predicted molecular weight: 32 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Use at an assay dependent concentration.
ELISA titre using peptide based assay: 1/62500.
Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction.
Belongs to the HMGN family.
Specifically targeted by its C-terminus to nucleosomes in euchromatin.
Nucleus. Associates with nucleosomes in euchromatin and is largely excluded from constitutive heterochromatin.
Information by UniProt
High mobility group nucleosome binding domain 5 antibody
High mobility group nucleosome-binding domain-containing protein 5 antibody
Anti-NSBP1 antibody (ab56031)参考文献
This product has been referenced in:
et al. Knockdown of the nucleosome binding protein 1 inhibits the growth and invasion of clear cell renal cell carcinoma cells in vitro and in vivo. J Exp Clin Cancer Res 31:22 (2012).
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