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ab31163 被引用在 69 文献中.

  • Guo C  et al. Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase Ce/Nrf2/HO-1 Pathway. Mol Neurobiol 54:833-845 (2017). PubMed: 26780453
  • Singh A  et al. Podophyllotoxin and Rutin Modulates Ionizing Radiation-Induced Oxidative Stress and Apoptotic Cell Death in Mice Bone Marrow and Spleen. Front Immunol 8:183 (2017). PubMed: 28289414
  • Arai A  et al. p62/SQSTM1 levels predicts radiotherapy resistance in hypopharyngeal carcinomas. Am J Cancer Res 7:881-891 (2017). IHC-P ; Human . PubMed: 28469960
  • Chen M  et al. Isoquercetin activates the ERK1/2-Nrf2 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro. Exp Ther Med 13:1353-1359 (2017). WB ; Rat . PubMed: 28413477
  • Shetty GA  et al. Chronic Oxidative Stress, Mitochondrial Dysfunction, Nrf2 Activation and Inflammation in the Hippocampus Accompany Heightened Systemic Inflammation and Oxidative Stress in an Animal Model of Gulf War Illness. Front Mol Neurosci 10:182 (2017). IHC-P ; Rat . PubMed: 28659758
  • Wei CC  et al. Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway. Sci Rep 7:717 (2017). WB . PubMed: 28386082
  • Cheng J  et al. Role of nuclear factor (erythroid-derived 2)-like 2 in the age-resistant properties of the glaucoma trabecular meshwork. Exp Ther Med 14:791-796 (2017). PubMed: 28673001
  • Zhang L  et al. Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways. Sci Rep 7:46763 (2017). WB, IHC . PubMed: 28429775
  • Akbari G  et al. The Hepatoprotective and MicroRNAs Downregulatory Effects of Crocin Following Hepatic Ischemia-Reperfusion Injury in Rats. Oxid Med Cell Longev 2017:1702967 (2017). PubMed: 28367266
  • Ugun-Klusek A  et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis 8:e2531 (2017). WB ; Mouse . PubMed: 28055010
  • Azimzadeh O  et al. A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers. Oncotarget 8:9067-9078 (2017). WB . PubMed: 27391067
  • Chaiprasongsuk A  et al. Activation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and Hispidulin. J Pharmacol Exp Ther 360:388-398 (2017). PubMed: 28011874
  • Yan B  et al. Sulforaphane prevents bleomycin-induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2-related factor-2 activation. Mol Med Rep 15:4005-4014 (2017). PubMed: 28487960
  • Wang Z  et al. Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2. Sci Rep 7:42095 (2017). PubMed: 28205579
  • Jin F  et al. Formononetin protects against acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. PLoS One 12:e0170900 (2017). PubMed: 28234915
  • Kao CJ  et al. The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity. Int J Mol Sci 18:N/A (2017). PubMed: 28534853
  • Katare PB  et al. Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats. Front Immunol 8:719 (2017). PubMed: 28690610
  • Han D  et al. The Neuroprotective Effects of Muscle-Derived Stem Cells via Brain-Derived Neurotrophic Factor in Spinal Cord Injury Model. Biomed Res Int 2017:1972608 (2017). WB ; Rat . PubMed: 28758111
  • Kakehashi A  et al. Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital. Oxid Med Cell Longev 2017:8541064 (2017). PubMed: 28785378
  • Yang X  et al. Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2. J Clin Invest 127:1505-1516 (2017). PubMed: 28287409
  • Chen M  et al. Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-ß-boswellic acid in combination on isoproterenol-induced myocardial injury in rats. Int J Mol Med 37:1501-10 (2016). IHC . PubMed: 27121241
  • Denis MC  et al. Apple peel polyphenols: a key player in the prevention and treatment of experimental inflammatory bowel disease. Clin Sci (Lond) 130:2217-2237 (2016). PubMed: 27630205
  • Ivankovic D  et al. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem 136:388-402 (2016). WB, IF . PubMed: 26509433
  • Han B  et al. The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease. Sci Rep 6:26928 (2016). WB, IF, IHC . PubMed: 27229886
  • Baek B  et al. Ellagic acid plays a protective role against UV-B-induced oxidative stress by up-regulating antioxidant components in human dermal fibroblasts. Korean J Physiol Pharmacol 20:269-77 (2016). WB . PubMed: 27162481
  • Chaisiriwong L  et al. A Case-Control Study of Involvement of Oxidative DNA Damage and Alteration of Antioxidant Defense System in Patients with Basal Cell Carcinoma: Modulation by Tumor Removal. Oxid Med Cell Longev 2016:5934024 (2016). IHC . PubMed: 27057281
  • Moshfegh C  et al. A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. Sci Rep 6:25104 (2016). IF . PubMed: 27157261
  • Zhou W  et al. Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fibrosis. Sci Rep 6:38646 (2016). WB ; Mouse . PubMed: 27982105
  • Shi X  et al. Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes. Int J Mol Med 38:123-30 (2016). WB, ICC/IF ; Rat . PubMed: 27220726
  • Li C  et al. Expression and correlation of NRF2, KEAP1, NQO-1 and HO-1 in advanced squamous cell carcinoma of the larynx and their association with clinicopathologic features. Mol Med Rep 14:5171-5179 (2016). IHC-P ; Apteronotus leptorhynchus . PubMed: 27840932
  • Feng CW  et al. Neuroprotective Effect of the Marine-Derived Compound 11-Dehydrosinulariolide through DJ-1-Related Pathway in In Vitro and In Vivo Models of Parkinson's Disease. Mar Drugs 14:N/A (2016). Rat . PubMed: 27763504
  • Guantes R  et al. Global variability in gene expression and alternative splicing is modulated by mitochondrial content. Genome Res 25:633-44 (2015). ICC ; Human . PubMed: 25800673
  • Yin XP  et al. Mechanisms underlying the perifocal neuroprotective effect of the Nrf2-ARE signaling pathway after intracranial hemorrhage. Drug Des Devel Ther 9:5973-86 (2015). WB . PubMed: 26604696
  • Vladimir-Kneževic S  et al. Hepatoprotective effects of Micromeria croatica ethanolic extract against CCl4-induced liver injury in mice. BMC Complement Altern Med 15:233 (2015). PubMed: 26174335
  • Cao S  et al. A novel mechanism for cytoprotection against hypoxic injury: d-opioid receptor-mediated increase in Nrf2 translocation. Br J Pharmacol 172:1869-81 (2015). PubMed: 25439010
  • Zhang J  et al. Comparisons of ethanol extracts of chinese propolis (poplar type) and poplar gums based on the antioxidant activities and molecular mechanism. Evid Based Complement Alternat Med 2015:307594 (2015). PubMed: 25802536
  • Zhang S  et al. Plumbagin protects against glucocorticoid-induced osteoporosis through Nrf-2 pathway. Cell Stress Chaperones 20:621-9 (2015). PubMed: 25939783
  • Han J  et al. Neuroprotective effects of salidroside on focal cerebral ischemia/reperfusion injury involve the nuclear erythroid 2-related factor 2 pathway. Neural Regen Res 10:1989-96 (2015). WB . PubMed: 26889188
  • Min SY  et al. Green Tea Epigallocatechin-3-Gallate Suppresses Autoimmune Arthritis Through Indoleamine-2,3-Dioxygenase Expressing Dendritic Cells and the Nuclear Factor, Erythroid 2-Like 2 Antioxidant Pathway. J Inflamm (Lond) 12:53 (2015). WB . PubMed: 26379475
  • Ye T  et al. Green tea polyphenol (-)-epigallocatechin-3-gallate restores Nrf2 activity and ameliorates crescentic glomerulonephritis. PLoS One 10:e0119543 (2015). WB . PubMed: 25785827
  • Yin XP  et al. Effects of that ATRA inhibits Nrf2-ARE pathway on glial cells activation after intracerebral hemorrhage. Int J Clin Exp Pathol 8:10436-43 (2015). PubMed: 26617752
  • Drozdzik A  et al. The role of Nrf2 in pathology of pleomorphic adenoma in parotid gland. Med Sci Monit 21:1243-8 (2015). IHC . PubMed: 25928388
  • Chen XY  et al. Cold stress initiates the Nrf2/UGT1A1/L-FABP signaling pathway in chickens. Poult Sci 94:2597-603 (2015). PubMed: 26453599
  • Ding Y  et al. Neuroprotection by acetyl-11-keto-ß-Boswellic acid, in ischemic brain injury involves the Nrf2/HO-1 defense pathway. Sci Rep 4:7002 (2014). IF . PubMed: 25384416
  • Rato L  et al. Pre-diabetes alters testicular PGC1-a/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress. Biochim Biophys Acta 1837:335-44 (2014). PubMed: 24361842
  • Guo C  et al. Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats. J Ethnopharmacol 151:660-6 (2014). WB, IHC-Fr ; Rat . PubMed: 24291152
  • Jo C  et al. Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52. Nat Commun 5:3496 (2014). PubMed: 24667209
  • Stack C  et al. Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity. Hum Mol Genet N/A:N/A (2014). WB ; Mouse . PubMed: 24556215
  • Mohamed MR  et al. Umbelliferone and daphnetin ameliorate carbon tetrachloride-induced hepatotoxicity in rats via nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1 expression. Environ Toxicol Pharmacol 38:531-41 (2014). Rat . PubMed: 25170823
  • Jin YN  et al. Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin. PLoS One 8:e57932 (2013). Mouse . PubMed: 23469253
  • Nanou A  et al. Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis. Mol Ther 21:1486-96 (2013). WB ; Mouse . PubMed: 23732987
  • Inui T  et al. Association of p62/SQSTM1 Excess and Oral Carcinogenesis. PLoS One 8:e74398 (2013). IHC-P ; Human . PubMed: 24086340
  • Lisk C  et al. Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. Free Radic Biol Med 63:264-73 (2013). WB, IHC-P, ICC/IF ; Rat . PubMed: 23722164
  • Abazeed ME  et al. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Res 73:6289-98 (2013). WB ; Human . PubMed: 23980093
  • Ma T  et al. Suppression of eIF2a kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci 16:1299-305 (2013). WB ; Mouse . PubMed: 23933749
  • Domitrovic R  et al. Differential hepatoprotective mechanisms of rutin and quercetin in CCl(4)-intoxicated BALB/cN mice. Acta Pharmacol Sin 33:1260-70 (2012). PubMed: 22902988
  • Bailey-Downs LC  et al. Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging. J Gerontol A Biol Sci Med Sci 67:313-29 (2012). WB ; Mouse . PubMed: 22021391
  • Kweider N  et al. A Role for Nrf2 in Redox Signalling of the Invasive Extravillous Trophoblast in Severe Early Onset IUGR Associated with Preeclampsia. PLoS One 7:e47055 (2012). IHC . PubMed: 23056578
  • Chao MW  et al. DEP induction of ROS in capillary-like endothelial tubes leads to VEGF-A expression. Toxicology 297:34-46 (2012). PubMed: 22507881
  • Kawabata K  et al. Dietary Crocin Inhibits Colitis and Colitis-Associated Colorectal Carcinogenesis in Male ICR Mice. Evid Based Complement Alternat Med 2012:820415 (2012). IHC . PubMed: 23326291
  • Pendyala S  et al. Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter. Free Radic Biol Med 50:1749-59 (2011). WB, ICC/IF ; Human, Mouse . PubMed: 21443946
  • Ungvari Z  et al. Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci 66:866-75 (2011). PubMed: 21622983
  • Ungvari Z  et al. Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol 301:H363-72 (2011). WB, IHC-Fr ; Rat . PubMed: 21602469
  • Ivanov AV  et al. Hepatitis C Virus Proteins Activate NRF2/ARE Pathway by Distinct ROS-Dependent and Independent Mechanisms in HUH7 Cells. PLoS One 6:e24957 (2011). WB ; Human . PubMed: 21931870
  • Sahin K  et al. Epigallocatechin-3-gallate prevents lipid peroxidation and enhances antioxidant defense system via modulating hepatic nuclear transcription factors in heat-stressed quails. Poult Sci 89:2251-8 (2010). PubMed: 20852116
  • Exil VJ  et al. Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans. PLoS One 5:e14228 (2010). WB ; Human . PubMed: 21151927
  • Schroeder EK  et al. Green tea epigallocatechin 3-gallate accumulates in mitochondria and displays a selective antiapoptotic effect against inducers of mitochondrial oxidative stress in neurons. Antioxid Redox Signal 11:469-80 (2009). WB ; Rat . PubMed: 18754708
  • Zhao X  et al. Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke 38:3280-6 (2007). PubMed: 17962605
  • Leonard MO  et al. Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J 20:2624-6 (2006). IHC-Fr ; Mouse . PubMed: 17142801

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