Anti-NR5A2 / LRH1抗体[EPR7000] (ab125034)


  • 产品名称Anti-NR5A2 / LRH1抗体[EPR7000]
    参阅全部 NR5A2 / LRH1 一抗
  • 描述
    兔单克隆抗体[EPR7000] to NR5A2 / LRH1
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human NR5A2/ LRH1.

  • 阳性对照
    • HeLa, BxPC3, HepG2 and MCF7 cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.



Our Abpromise guarantee covers the use of ab125034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 65 kDa (predicted molecular weight: 61 kDa).Can be blocked with NR5A2 / LRH1 peptide (ab169741).
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
    • 组织特异性Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells.
    • 序列相似性Belongs to the nuclear hormone receptor family. NR5 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Alpha-1-fetoprotein transcription factor antibody
      • B1-binding factor antibody
      • B1F antibody
      • B1F2 antibody
      • CPF antibody
      • CYP7A promoter-binding factor antibody
      • FTF antibody
      • FTZ F1 antibody
      • FTZ F1beta antibody
      • FTZ-F1 antibody
      • FTZ-F1beta antibody
      • hB1F 2 antibody
      • hB1F antibody
      • hB1F-2 antibody
      • Hepatocytic transcription factor antibody
      • Liver receptor homolog 1 antibody
      • LRH-1 antibody
      • LRH1 antibody
      • Nr5a2 antibody
      • NR5A2_HUMAN antibody
      • Nuclear receptor subfamily 5 group A member 2 antibody
      see all

    Anti-NR5A2 / LRH1 antibody [EPR7000] 图像

    • All lanes : Anti-NR5A2 / LRH1 antibody [EPR7000] (ab125034) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : BxPC3 cell lysate
      Lane 3 : HepG2 cell lysate
      Lane 4 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.

      HRP labelled goat anti rabbit at 1/2000 dilution

      Predicted band size : 61 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)

    Anti-NR5A2 / LRH1 antibody [EPR7000] (ab125034)参考文献

    ab125034 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab125034.
    Please use the links above to contact us or submit feedback about this product.