概述

  • 产品名称Anti-NPR2L抗体
    参阅全部 NPR2L 一抗
  • 描述
    兔多克隆抗体to NPR2L
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal region amino acids 287-336 (

    SLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTRE

    ) of Human NPR2L (NP_006536)

  • 阳性对照
    • NCI-H226 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab98250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
  • 组织特异性Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.
  • 序列相似性Belongs to the NPR2 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2810446G01Rik antibody
    • G21 protein antibody
    • Gene 21 protein antibody
    • Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody
    • Homologous to yeast nitrogen permease antibody
    • Nitrogen permease regulator 2-like protein antibody
    • Nitrogen permease regulator-like 2 (S. cerevisiae) antibody
    • NPR 2L antibody
    • NPR L2 antibody
    • NPR like 2 antibody
    • NPR2 antibody
    • NPR2 like antibody
    • NPR2-like protein antibody
    • NPR2L antibody
    • NPRL 2 antibody
    • NPRL2 antibody
    • NPRL2_HUMAN antibody
    • Tumor suppressor candidate 4 antibody
    • TUSC 4 antibody
    • TUSC 4 protein antibody
    • TUSC4 antibody
    • TUSC4 protein antibody
    see all

Anti-NPR2L antibody 图像

  • Anti-NPR2L antibody (ab98250) at 1 µg/ml + NCI-H226 cell lysate at 10 µg

    Predicted band size : 44 kDa

Anti-NPR2L antibody (ab98250)参考文献

ab98250 has not yet been referenced specifically in any publications.

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