Anti-NPHS2抗体, prediluted (ab82107)

概述

  • 产品名称Anti-NPHS2抗体, prediluted
    参阅全部 NPHS2 一抗
  • 描述
    兔多克隆抗体to NPHS2, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to the internal region of human NPHS2

  • 阳性对照
    • Kidney tissue

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab82107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use. Incubate for 30 mins at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol by boiling tissue section in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
    • 组织特异性Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli.
    • 疾病相关Defects in NPHS2 are the cause of nephrotic syndrome type 2 (NPHS2) [MIM:600995]. It is a renal disorder characterized clinically by childhood onset of proteinuria, hypoalbuminemia, hyperlipidemia, and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. The disorder is resistant to steroid treatment and progresses to end-stage renal failure in the first or second decades. Some patients show later onset of the disorder.
    • 序列相似性Belongs to the band 7/mec-2 family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Nephrosis 2, idiopathic, steroid resistant (podocin) antibody
      • nephrosis 2, idiopathic, steroid resistant antibody
      • NPHS2 antibody
      • NPHS2 gene antibody
      • PDCN antibody
      • PODO_HUMAN antibody
      • Podocin antibody
      • SRN1 antibody
      see all

    Anti-NPHS2 antibody, prediluted 图像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human kidney tissue using prediluted ab82107.

    Anti-NPHS2 antibody, prediluted (ab82107)参考文献

    ab82107 has not yet been referenced specifically in any publications.

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    I have issued you the testing discount codes for ab82108 and ab82107 for testing in rat and pig. Please see below for the information.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"