Anti-NOX2/gp91phox抗体(ab106940)
Key features and details
- Goat polyclonal to NOX2/gp91phox
- Suitable for: IHC
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-NOX2/gp91phox抗体
参阅全部 NOX2/gp91phox 一抗 -
描述
山羊多克隆抗体to NOX2/gp91phox -
宿主
Goat -
经测试应用
适用于: IHCmore details -
种属反应性
与反应: Human
预测可用于: Dog -
免疫原
Synthetic peptide corresponding to Human NOX2/gp91phox aa 151-163 (internal sequence).
Sequence:C-SYLNFARKRIKNP
Database link: P04839 -
阳性对照
- IHC-P: Human placenta tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106940于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC |
Use a concentration of 2 - 4 µg/ml.
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说明 |
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IHC
Use a concentration of 2 - 4 µg/ml. |
靶标
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功能
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. -
疾病相关
Defects in CYBB are a cause of chronic granulomatous disease X-linked (XCGD) [MIM:306400]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections. -
序列相似性
Contains 1 FAD-binding FR-type domain.
Contains 1 ferric oxidoreductase domain. -
翻译后修饰
Glycosylated. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1536 Human
- Omim: 300481 Human
- SwissProt: P04839 Human
- Unigene: 292356 Human
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别名
- AMCBX2 antibody
- CGD antibody
- CGD91-phox antibody
see all
数据表及文件
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Datasheet download
文献 (0)
ab106940 尚未被引用在任何文献中。