Anti-NOX2/gp91phox抗体(ab106940)

概述

  • 产品名称Anti-NOX2/gp91phox抗体
    参阅全部 NOX2/gp91phox 一抗
  • 描述
    山羊多克隆抗体to NOX2/gp91phox
  • 经测试应用适用于: IHC, WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide corresponding to Human NOX2/gp91phox aa 151-163 (internal sequence).
    Sequence:

    C-SYLNFARKRIKNP


    Database link: P04839

  • 阳性对照
    • Human Peripheral Blood Mononucleocytes lysate.

性能

应用

Our Abpromise guarantee covers the use of ab106940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC Use a concentration of 2 - 4 µg/ml.
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 65.3 kDa).
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:2,000.

靶标

  • 功能Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
  • 疾病相关Defects in CYBB are a cause of chronic granulomatous disease X-linked (XCGD) [MIM:306400]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
  • 序列相似性Contains 1 FAD-binding FR-type domain.
    Contains 1 ferric oxidoreductase domain.
  • 翻译后修饰Glycosylated.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AMCBX2 antibody
    • CGD antibody
    • CGD91-phox antibody
    • CY24B_HUMAN antibody
    • CYBB antibody
    • Cytochrome b 245, beta polypeptide antibody
    • Cytochrome b(558) beta chain antibody
    • Cytochrome b(558) subunit beta antibody
    • Cytochrome b-245 heavy chain antibody
    • Cytochrome b558 subunit beta antibody
    • GP91 PHOX antibody
    • gp91-1 antibody
    • gp91-phox antibody
    • GP91PHOX antibody
    • Heme-binding membrane glycoprotein gp91phox antibody
    • NADPH oxidase 2 antibody
    • Neutrophil cytochrome b 91 kDa polypeptide antibody
    • NOX2 antibody
    • p22 phagocyte B-cytochrome antibody
    • P91 PHOX antibody
    • p91-PHOX antibody
    • Superoxide-generating NADPH oxidase heavy chain subunit antibody
    see all

Anti-NOX2/gp91phox antibody 图像

  • Immunohistochemical analysis of paraffin embedded Human Spleen tissue labeling NOX2/gp91phox with ab106940 at 2 ug/ml. Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). The HRP-staining procedure was used for detection.

  • Anti-NOX2/gp91phox antibody (ab106940) at 0.03 µg/ml + Peripheral Blood Mononucleocytes lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 65.3 kDa

Anti-NOX2/gp91phox antibody (ab106940)参考文献

ab106940 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106940.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"